An inbred line of transgenic mice expressing an internally deleted gene for type II procollagen (COL2A1). Young mice have a variable phenotype of a chondrodysplasia and older mice have osteoarthritic changes in joints.

অনুরূপ উপাদানগুলি

• Expression of a partially deleted gene of human type II procollagen (COL2A1) in transgenic mice produces a chondrodysplasia.
  অনুযায়ী: Vandenberg, P, অন্যান্য
  প্রকাশিত: (1991)
• Transgenic mice expressing a partially deleted gene for type I procollagen (COL1A1). A breeding line with a phenotype of spontaneous fractures and decreased bone collagen and mineral.
  অনুযায়ী: Pereira, R, অন্যান্য
  প্রকাশিত: (1993)
• Single base mutation in the type II procollagen gene (COL2A1) as a cause of primary osteoarthritis associated with a mild chondrodysplasia.
  অনুযায়ী: Ala-Kokko, L, অন্যান্য
  প্রকাশিত: (1990)
• Phenotypic variability and incomplete penetrance of spontaneous fractures in an inbred strain of transgenic mice expressing a mutated collagen gene (COL1A1).
  অনুযায়ী: Pereira, R, অন্যান্য
  প্রকাশিত: (1994)
• Lack of a phenotype in transgenic mice aberrantly expressing COL2A1 mRNA because of highly selective post-transcriptional down-regulation.
  অনুযায়ী: Yuan, C M, অন্যান্য
  প্রকাশিত: (2000)