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Synthesis of recombinant human procollagen II in a stably transfected tumour cell line (HT1080).

Apparently because the biosynthetic pathways involve eight or more highly specific post-translational enzymes, it has been difficult to obtain expression of genes for fibrillar collagens in recombinant systems. Here two constructs of the human gene for procollagen II (COL2A1) were prepared, one with...

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Autors principals: Fertala, A, Sieron, A L, Ganguly, A, Li, S W, Ala-Kokko, L, Anumula, K R, Prockop, D J
Format: Artigo
Idioma:Inglês
Publicat: 1994
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1137979/
https://ncbi.nlm.nih.gov/pubmed/8129728
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