Nuclear Tau and Its Potential Role in Alzheimer’s Disease

بواسطة Bukar Maina, Mahmoud, Al-Hilaly, Youssra K., Serpell, Louise C.
الحاوية / القاعدة Biomolecules (2016)

Metal- and UV- Catalyzed Oxidation Results in Trapped Amyloid-β Intermediates Revealing that Self-Assembly Is Required for Aβ-Induced Cytotoxicity

بواسطة Maina, Mahmoud B., Burra, Gunasekhar, Al-Hilaly, Youssra K., Mengham, Kurtis, Fennell, Kate, Serpell, Louise C.
الحاوية / القاعدة iScience (2020)

The Molecular Basis for Apolipoprotein E4 as the Major Risk Factor for Late-Onset Alzheimer's Disease

بواسطة Raulin, Ana-Caroline, Kraft, Lucas, Al-Hilaly, Youssra K., Xue, Wei-Feng, McGeehan, John E., Atack, John R., Serpell, Louise
الحاوية / القاعدة J Mol Biol (2019)

Tau Filament Self-Assembly and Structure: Tau as a Therapeutic Target

بواسطة Oakley, Sebastian S., Maina, Mahmoud B., Marshall, Karen E., Al-Hilaly, Youssra K., Harrington, Charlie R., Wischik, Claude M., Serpell, Louise C.
الحاوية / القاعدة Front Neurol (2020)

Oxidative Stress Conditions Result in Trapping of PHF-Core Tau (297–391) Intermediates

بواسطة Maina, Mahmoud B., Al-Hilaly, Youssra K., Burra, Gunasekhar, Rickard, Janet E., Harrington, Charles R., Wischik, Claude M., Serpell, Louise C.
الحاوية / القاعدة Cells (2021)

The involvement of dityrosine crosslinking in α-synuclein assembly and deposition in Lewy Bodies in Parkinson’s disease

بواسطة Al-Hilaly, Youssra K., Biasetti, Luca, Blakeman, Ben J. F., Pollack, Saskia J., Zibaee, Shahin, Abdul-Sada, Alaa, Thorpe, Julian R., Xue, Wei-Feng, Serpell, Louise C.
الحاوية / القاعدة Sci Rep (2016)

Paired Helical Filament-Forming Region of Tau (297–391) Influences Endogenous Tau Protein and Accumulates in Acidic Compartments in Human Neuronal Cells

بواسطة Pollack, Saskia J., Trigg, Jasmine, Khanom, Tahmida, Biasetti, Luca, Marshall, Karen E., Al-Hilaly, Youssra K., Rickard, Janet E., Harrington, Charles R., Wischik, Claude M., Serpell, Louise C.
الحاوية / القاعدة J Mol Biol (2020)

Using chirality to influence supramolecular gelation

بواسطة McAulay, Kate, Dietrich, Bart, Su, Hao, Scott, Michael T., Rogers, Sarah, Al-Hilaly, Youssra K., Cui, Honggang, Serpell, Louise C., Seddon, Annela M., Draper, Emily R., Adams, Dave J.
الحاوية / القاعدة Chem Sci (2019)

A central role for dityrosine crosslinking of Amyloid-β in Alzheimer’s disease

بواسطة Al-Hilaly, Youssra K, Williams, Thomas L, Stewart-Parker, Maris, Ford, Lenzie, Skaria, Eldhose, Cole, Michael, Bucher, William Grant, Morris, Kyle L, Sada, Alaa Abdul, Thorpe, Julian R, Serpell, Louise C
منشور في 2013

Tau (297‐391) forms filaments that structurally mimic the core of paired helical filaments in Alzheimer’s disease brain

بواسطة Al‐Hilaly, Youssra K., Foster, Bronwen E., Biasetti, Luca, Lutter, Liisa, Pollack, Saskia J., Rickard, Janet E., Storey, John M. D., Harrington, Charles R., Xue, Wei‐Feng, Wischik, Claude M., Serpell, Louise C.
الحاوية / القاعدة FEBS Lett (2019)

The elusive tau molecular structures: can we translate the recent breakthroughs into new targets for intervention?

بواسطة Fichou, Yann, Al-Hilaly, Youssra K., Devred, François, Smet-Nocca, Caroline, Tsvetkov, Philipp O., Verelst, Joke, Winderickx, Joris, Geukens, Nick, Vanmechelen, Eugeen, Perrotin, Audrey, Serpell, Louise, Hanseeuw, Bernard J, Medina, Miguel, Buée, Luc, Landrieu, Isabelle
الحاوية / القاعدة Acta Neuropathol Commun (2019)

The CDR1 and Other Regions of Immunoglobulin Light Chains are Hot Spots for Amyloid Aggregation

بواسطة Ruiz-Zamora, Robin Axel, Guillaumé, Simon, Al-Hilaly, Youssra K., Al-Garawi, Zahraa, Rodríguez-Alvarez, Francisco Javier, Zavala-Padilla, Guadalupe, Pérez-Carreón, Julio I., Rodríguez-Ambriz, Sandra L., Herrera, Guillermo A., Becerril-Luján, Baltazar, Ochoa-Leyva, Adrián, Melendez-Zajgla, Jorge, Serpell, Louise, del Pozo-Yauner, Luis
الحاوية / القاعدة Sci Rep (2019)