Nuclear Tau and Its Potential Role in Alzheimer’s Disease

অনুযায়ী Bukar Maina, Mahmoud, Al-Hilaly, Youssra K., Serpell, Louise C.
প্রকাশিত Biomolecules (2016)

Metal- and UV- Catalyzed Oxidation Results in Trapped Amyloid-β Intermediates Revealing that Self-Assembly Is Required for Aβ-Induced Cytotoxicity

অনুযায়ী Maina, Mahmoud B., Burra, Gunasekhar, Al-Hilaly, Youssra K., Mengham, Kurtis, Fennell, Kate, Serpell, Louise C.
প্রকাশিত iScience (2020)

The Molecular Basis for Apolipoprotein E4 as the Major Risk Factor for Late-Onset Alzheimer's Disease

অনুযায়ী Raulin, Ana-Caroline, Kraft, Lucas, Al-Hilaly, Youssra K., Xue, Wei-Feng, McGeehan, John E., Atack, John R., Serpell, Louise
প্রকাশিত J Mol Biol (2019)

Tau Filament Self-Assembly and Structure: Tau as a Therapeutic Target

অনুযায়ী Oakley, Sebastian S., Maina, Mahmoud B., Marshall, Karen E., Al-Hilaly, Youssra K., Harrington, Charlie R., Wischik, Claude M., Serpell, Louise C.
প্রকাশিত Front Neurol (2020)

Oxidative Stress Conditions Result in Trapping of PHF-Core Tau (297–391) Intermediates

অনুযায়ী Maina, Mahmoud B., Al-Hilaly, Youssra K., Burra, Gunasekhar, Rickard, Janet E., Harrington, Charles R., Wischik, Claude M., Serpell, Louise C.
প্রকাশিত Cells (2021)

The involvement of dityrosine crosslinking in α-synuclein assembly and deposition in Lewy Bodies in Parkinson’s disease

অনুযায়ী Al-Hilaly, Youssra K., Biasetti, Luca, Blakeman, Ben J. F., Pollack, Saskia J., Zibaee, Shahin, Abdul-Sada, Alaa, Thorpe, Julian R., Xue, Wei-Feng, Serpell, Louise C.
প্রকাশিত Sci Rep (2016)

A critical role for the self-assembly of Amyloid-β1-42 in neurodegeneration

অনুযায়ী Marshall, Karen E., Vadukul, Devkee M., Dahal, Liza, Theisen, Alina, Fowler, Milena W., Al-Hilaly, Youssra, Ford, Lenzie, Kemenes, György, Day, Iain J., Staras, Kevin, Serpell, Louise C.
প্রকাশিত Sci Rep (2016)

Paired Helical Filament-Forming Region of Tau (297–391) Influences Endogenous Tau Protein and Accumulates in Acidic Compartments in Human Neuronal Cells

অনুযায়ী Pollack, Saskia J., Trigg, Jasmine, Khanom, Tahmida, Biasetti, Luca, Marshall, Karen E., Al-Hilaly, Youssra K., Rickard, Janet E., Harrington, Charles R., Wischik, Claude M., Serpell, Louise C.
প্রকাশিত J Mol Biol (2020)

Using chirality to influence supramolecular gelation

অনুযায়ী McAulay, Kate, Dietrich, Bart, Su, Hao, Scott, Michael T., Rogers, Sarah, Al-Hilaly, Youssra K., Cui, Honggang, Serpell, Louise C., Seddon, Annela M., Draper, Emily R., Adams, Dave J.
প্রকাশিত Chem Sci (2019)

A central role for dityrosine crosslinking of Amyloid-β in Alzheimer’s disease

অনুযায়ী Al-Hilaly, Youssra K, Williams, Thomas L, Stewart-Parker, Maris, Ford, Lenzie, Skaria, Eldhose, Cole, Michael, Bucher, William Grant, Morris, Kyle L, Sada, Alaa Abdul, Thorpe, Julian R, Serpell, Louise C
প্রকাশিত 2013

Tau (297‐391) forms filaments that structurally mimic the core of paired helical filaments in Alzheimer’s disease brain

অনুযায়ী Al‐Hilaly, Youssra K., Foster, Bronwen E., Biasetti, Luca, Lutter, Liisa, Pollack, Saskia J., Rickard, Janet E., Storey, John M. D., Harrington, Charles R., Xue, Wei‐Feng, Wischik, Claude M., Serpell, Louise C.
প্রকাশিত FEBS Lett (2019)

The elusive tau molecular structures: can we translate the recent breakthroughs into new targets for intervention?

অনুযায়ী Fichou, Yann, Al-Hilaly, Youssra K., Devred, François, Smet-Nocca, Caroline, Tsvetkov, Philipp O., Verelst, Joke, Winderickx, Joris, Geukens, Nick, Vanmechelen, Eugeen, Perrotin, Audrey, Serpell, Louise, Hanseeuw, Bernard J, Medina, Miguel, Buée, Luc, Landrieu, Isabelle
প্রকাশিত Acta Neuropathol Commun (2019)

The CDR1 and Other Regions of Immunoglobulin Light Chains are Hot Spots for Amyloid Aggregation

অনুযায়ী Ruiz-Zamora, Robin Axel, Guillaumé, Simon, Al-Hilaly, Youssra K., Al-Garawi, Zahraa, Rodríguez-Alvarez, Francisco Javier, Zavala-Padilla, Guadalupe, Pérez-Carreón, Julio I., Rodríguez-Ambriz, Sandra L., Herrera, Guillermo A., Becerril-Luján, Baltazar, Ochoa-Leyva, Adrián, Melendez-Zajgla, Jorge, Serpell, Louise, del Pozo-Yauner, Luis
প্রকাশিত Sci Rep (2019)