Role of the amino terminal RHAU-specific motif in the recognition and resolution of guanine quadruplex-RNA by the DEAH-box RNA helicase RHAU

Por Lattmann, Simon, Giri, Banabihari, Vaughn, James P., Akman, Steven A., Nagamine, Yoshikuni
Publicado em 2010

Mutagenicity of Ochratoxin A and Its Hydroquinone Metabolite in the SupF Gene of the Mutation Reporter Plasmid Ps189

Por Akman, Steven A., Adams, Marissa, Case, Doug, Park, Gyungse, Manderville, Richard A.
Publicado em 2012

The DEAH-box RNA helicase RHAU binds an intramolecular RNA G-quadruplex in TERC and associates with telomerase holoenzyme

Por Lattmann, Simon, Stadler, Michael B., Vaughn, James P., Akman, Steven A., Nagamine, Yoshikuni
Publicado em 2011

Oral paricalcitol (19-nor-1,25-dihydroxyvitamin D(2)) in women receiving chemotherapy for metastatic breast cancer: A feasibility trial

Por Lawrence, Julia A., Akman, Steven A., Melin, Susan A., Case, L. Douglas, Schwartz, Gary G.
Publicado em 2013

G4 Resolvase 1 Binds Both DNA and RNA Tetramolecular Quadruplex with High Affinity and Is the Major Source of Tetramolecular Quadruplex G4-DNA and G4-RNA Resolving Activity in He...

Por Creacy, Steven D., Routh, Eric D., Iwamoto, Fumiko, Nagamine, Yoshikuni, Akman, Steven A., Vaughn, James P.
Publicado em 2008

Oxidative DNA Base Damage in MCF-10A Breast Epithelial Cells at Clinically Achievable Concentrations of Doxorubicin

Por Gajewski, Ewa, Gaur, Shikha, Akman, Steven A., Matsumoto, Linda, van Balgooy, Josephus N.A., Doroshow, James H.
Publicado em 2007

A G-quadruplex DNA-affinity Approach for Purification of Enzymatically Active G4 Resolvase1

Por Routh, Eric D., Creacy, Steven D., Beerbower, Peter E., Akman, Steven A., Vaughn, James P., Smaldino, Philip J.
Publicado no J Vis Exp (2017)

Differential cytotoxic and radiosensitizing effects of silver nanoparticles on triple-negative breast cancer and non-triple-negative breast cells

Por Swanner, Jessica, Mims, Jade, Carroll, David L, Akman, Steven A, Furdui, Cristina M, Torti, Suzy V, Singh, Ravi N
Publicado no Int J Nanomedicine (2015)

Mutational Dissection of Telomeric DNA Binding Requirements of G4 Resolvase 1 Shows that G4-Structure and Certain 3’-Tail Sequences Are Sufficient for Tight and Complete Binding

Por Smaldino, Philip J., Routh, Eric D., Kim, Jung H., Giri, Banabihari, Creacy, Steven D., Hantgan, Roy R., Akman, Steven A., Vaughn, James P.
Publicado no PLoS One (2015)

Polygenic model of DNA repair genetic polymorphisms in human breast cancer risk

Por Smith, Tasha R., Levine, Edward A., Freimanis, Rita I., Akman, Steven A., Allen, Glenn O., Hoang, Kimberly N., Liu-Mares, Wen, Hu, Jennifer J.
Publicado em 2008

Fatty Acid Metabolites in Rapidly Proliferating Breast Cancer

Por O’Flaherty, Joseph T., Wooten, Rhonda E., Samuel, Michael P., Thomas, Michael J., Levine, Edward A., Case, L. Douglas, Akman, Steven A., Edwards, Iris J.
Publicado em 2013

The Core Control System of Intracellular Iron Homeostasis: A Mathematical Model

Por Chifman, J., Kniss, A., Neupane, P., Williams, I., Leung, B., Deng, Z., Mendes, P., Hower, V., Torti, F. M., Akman, S. A., Torti, S. V., Laubenbacher, R.
Publicado em 2012

G4 Resolvase 1 tightly binds and unwinds unimolecular G4-DNA

Por Giri, Banabihari, Smaldino, Philip J., Thys, Ryan G., Creacy, Steven D., Routh, Eric D., Hantgan, Roy R., Lattmann, Simon, Nagamine, Yoshikuni, Akman, Steven A., Vaughn, James P.
Publicado em 2011

Yin Yang 1 contains G-quadruplex structures in its promoter and 5′-UTR and its expression is modulated by G4 resolvase 1

Por Huang, Weiwei, Smaldino, Philip J., Zhang, Qiang, Miller, Lance D., Cao, Paul, Stadelman, Kristin, Wan, Meimei, Giri, Banabihari, Lei, Ming, Nagamine, Yoshikuni, Vaughn, James P., Akman, Steven A., Sui, Guangchao
Publicado em 2012

Activated Oncogenic Pathway Modifies Iron Network in Breast Epithelial Cells: A Dynamic Modeling Perspective

Por Chifman, Julia, Arat, Seda, Deng, Zhiyong, Lemler, Erica, Pino, James C., Harris, Leonard A., Kochen, Michael A., Lopez, Carlos F., Akman, Steven A., Torti, Frank M., Torti, Suzy V., Laubenbacher, Reinhard
Publicado no PLoS Comput Biol (2017)

Yin Yang 1 Plays an Essential Role in Breast Cancer and Negatively Regulates p27

Por Wan, Meimei, Huang, Weiwei, Kute, Timothy E., Miller, Lance D., Zhang, Qiang, Hatcher, Heather, Wang, Jingxuan, Stovall, Daniel B., Russell, Gregory B., Cao, Paul D., Deng, Zhiyong, Wang, Wei, Zhang, Qingyuan, Lei, Ming, Torti, Suzy V., Akman, Steven A., Sui, Guangchao
Publicado em 2012