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The Core Control System of Intracellular Iron Homeostasis: A Mathematical Model

Iron is a metal essential for cellular metabolism. However, excess iron available for reactions contributes to the formation of dangerous reactive oxygen species, such as the hydroxyl radical, via the Fenton reaction. Therefore, intracellular iron levels are tightly constrained by a control system o...

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Detalhes bibliográficos
Main Authors: Chifman, J., Kniss, A., Neupane, P., Williams, I., Leung, B., Deng, Z., Mendes, P., Hower, V., Torti, F. M., Akman, S. A., Torti, S. V., Laubenbacher, R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307864/
https://ncbi.nlm.nih.gov/pubmed/22286016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2012.01.024
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