A Phosphoinositide 3-Kinase/Phospholipase Cgamma1 Pathway Regulates Fibroblast Growth Factor-Induced Capillary Tube Formation

Por Maffucci, Tania, Raimondi, Claudio, Abu-Hayyeh, Shadi, Dominguez, Veronica, Sala, Gianluca, Zachary, Ian, Falasca, Marco
Publicado em 2009

A progesterone-brown fat axis is involved in regulating fetal growth

Por McIlvride, Saraid, Mushtaq, Aleena, Papacleovoulou, Georgia, Hurling, Chloe, Steel, Jennifer, Jansen, Eugène, Abu-Hayyeh, Shadi, Williamson, Catherine
Publicado no Sci Rep (2017)

Changes in LXR signaling influence early-pregnancy lipogenesis and protect against dysregulated fetoplacental lipid homeostasis

Por Nikolova, Vanya, Papacleovoulou, Georgia, Bellafante, Elena, Borges Manna, Luiza, Jansen, Eugene, Baron, Silvère, Abu-Hayyeh, Shadi, Parker, Malcolm, Williamson, Catherine
Publicado no Am J Physiol Endocrinol Metab (2017)

Bile Acid-Induced Arrhythmia Is Mediated by Muscarinic M(2) Receptors in Neonatal Rat Cardiomyocytes

Por Sheikh Abdul Kadir, Siti H., Miragoli, Michele, Abu-Hayyeh, Shadi, Moshkov, Alexey V., Xie, Qilian, Keitel, Verena, Nikolaev, Viacheslav O., Williamson, Catherine, Gorelik, Julia
Publicado em 2010

Inhibition of Na(+)-Taurocholate Co-transporting Polypeptide-mediated Bile Acid Transport by Cholestatic Sulfated Progesterone Metabolites

Por Abu-Hayyeh, Shadi, Martinez-Becerra, Pablo, Sheikh Abdul Kadir, Siti H., Selden, Clare, Romero, Marta R., Rees, Myrddin, Marschall, Hanns-Ulrich, Marin, Jose J. G., Williamson, Catherine
Publicado em 2010

Embryonic stem cell-derived cardiomyocytes as a model to study fetal arrhythmia related to maternal disease

Por Kadir, Siti H Sheikh Abdul, Ali, Nadire N, Mioulane, Maxime, Brito-Martins, Marta, Abu-Hayyeh, Shadi, Foldes, Gabor, Moshkov, Alexey V, Williamson, Catherine, Harding, Sian E, Gorelik, Julia
Publicado no J Cell Mol Med (2009)

LKB1 is required for hepatic bile acid transport and canalicular membrane integrity in mice

Por Woods, Angela, Heslegrave, Amanda J., Muckett, Phillip J., Levene, Adam P., Clements, Melanie, Mobberley, Margaret, Ryder, Timothy A., Abu-Hayyeh, Shadi, Williamson, Catherine, Goldin, Robert D., Ashworth, Alan, Withers, Dominic J., Carling, David
Publicado em 2011

Intrahepatic Cholestasis of Pregnancy Levels of Sulfated Progesterone Metabolites Inhibit Farnesoid X Receptor Resulting in a Cholestatic Phenotype

Por Abu-Hayyeh, Shadi, Papacleovoulou, Georgia, Lövgren-Sandblom, Anita, Tahir, Mehreen, Oduwole, Olayiwola, Jamaludin, Nurul Akmal, Ravat, Sabiha, Nikolova, Vanya, Chambers, Jenny, Selden, Clare, Rees, Myrddin, Marschall, Hanns-Ulrich, Parker, Malcolm G, Williamson, Catherine
Publicado em 2013

Maternal cholestasis during pregnancy programs metabolic disease in offspring

Por Papacleovoulou, Georgia, Abu-Hayyeh, Shadi, Nikolopoulou, Evanthia, Briz, Oscar, Owen, Bryn M., Nikolova, Vanya, Ovadia, Caroline, Huang, Xiao, Vaarasmaki, Marja, Baumann, Marc, Jansen, Eugene, Albrecht, Christiane, Jarvelin, Marjo-Riitta, Marin, Jose J.G., Knisely, A.S., Williamson, Catherine
Publicado em 2013

Ursodeoxycholic acid improves feto-placental and offspring metabolic outcomes in hypercholanemic pregnancy

Por Borges Manna, Luiza, Papacleovoulou, Georgia, Flaviani, Flavia, Pataia, Vanessa, Qadri, Asaad, Abu-Hayyeh, Shadi, McIlvride, Saraid, Jansen, Eugene, Dixon, Peter, Chambers, Jennifer, Vazquez-Lopez, Marta, Wahlström, Annika, Kitaba, Negusse, Marschall, Hanns-Ulrich, Godfrey, Keith M., Lillycrop, Karen, Williamson, Catherine
Publicado no Sci Rep (2020)

Enhanced Microbial Bile Acid Deconjugation and Impaired Ileal Uptake in Pregnancy Repress Intestinal Regulation of Bile Acid Synthesis

Por Ovadia, Caroline, Perdones‐Montero, Alvaro, Spagou, Konstantina, Smith, Ann, Sarafian, Magali H., Gomez‐Romero, Maria, Bellafante, Elena, Clarke, Louise C.D., Sadiq, Fouzia, Nikolova, Vanya, Mitchell, Alice, Dixon, Peter H., Santa‐Pinter, Natalie, Wahlström, Annika, Abu‐Hayyeh, Shadi, Walters, Julian R.F., Marschall, Hanns‐Ulrich, Holmes, Elaine, Marchesi, Julian R., Williamson, Catherine
Publicado no Hepatology (2019)

Prognostic and mechanistic potential of progesterone sulfates in intrahepatic cholestasis of pregnancy and pruritus gravidarum

Por Abu‐Hayyeh, Shadi, Ovadia, Caroline, Lieu, TinaMarie, Jensen, Dane D., Chambers, Jenny, Dixon, Peter H., Lövgren‐Sandblom, Anita, Bolier, Ruth, Tolenaars, Dagmar, Kremer, Andreas E., Syngelaki, Argyro, Noori, Muna, Williams, David, Marin, Jose J.G., Monte, Maria J., Nicolaides, Kypros H., Beuers, Ulrich, Oude‐Elferink, Ronald, Seed, Paul T., Chappell, Lucy, Marschall, Hanns‐Ulrich, Bunnett, Nigel W., Williamson, Catherine
Publicado no Hepatology (2015)