Mirvetuximab Soravtansine (IMGN853), a Folate Receptor Alpha–Targeting Antibody-Drug Conjugate, Potentiates the Activity of Standard of Care Therapeutics in Ovarian Cancer Models()...

door Ponte, Jose F., Ab, Olga, Lanieri, Leanne, Lee, Jenny, Coccia, Jennifer, Bartle, Laura M., Themeles, Marian, Zhou, Yinghui, Pinkas, Jan, Ruiz-Soto, Rodrigo
Gepubliceerd in Neoplasia (2016)

Antibody Co-Administration Can Improve Systemic and Local Distribution of Antibody Drug Conjugates to Increase In Vivo Efficacy

door Ponte, Jose F., Lanieri, Leanne, Khera, Eshita, Laleau, Rassol, Ab, Olga, Espelin, Christopher, Kohli, Neeraj, Matin, Bahar, Setiady, Yulius, Miller, Michael L., Keating, Thomas A., Chari, Ravi, Pinkas, Jan, Gregory, Richard, Thurber, Greg M.
Gepubliceerd in Mol Cancer Ther (2020)

A CD123-targeting antibody-drug conjugate, IMGN632, designed to eradicate AML while sparing normal bone marrow cells

door Kovtun, Yelena, Jones, Gregory E., Adams, Sharlene, Harvey, Lauren, Audette, Charlene A., Wilhelm, Alan, Bai, Chen, Rui, Lingyun, Laleau, Rassol, Liu, Fenghua, Ab, Olga, Setiady, Yulius, Yoder, Nicholas C., Goldmacher, Victor S., Chari, Ravi V. J., Pinkas, Jan, Chittenden, Thomas
Gepubliceerd in Blood Adv (2018)

Synthesis of Highly Potent N-10 Amino-Linked DNA-Alkylating Indolinobenzodiazepine Antibody–Drug Conjugates (ADCs)

door Archer, Katie E., Reid, Emily E., Shizuka, Manami, Woods, James, Harris, Luke, Maloney, Erin K., Bartle, Laura M., Ab, Olga, Wilhelm, Alan, Setiady, Yulius, Ponte, Jose F., Singh, Rajeeva, Keating, Thomas A., Chari, Ravi V. J., Miller, Michael L.
Gepubliceerd in ACS Med Chem Lett (2019)

Peptide-Cleavable Self-immolative Maytansinoid Antibody–Drug Conjugates Designed To Provide Improved Bystander Killing

door Costoplus, Juliet A., Veale, Karen H., Qiu, Qifeng, Ponte, Jose F., Lanieri, Leanne, Setiady, Yulius, Dong, Ling, Skaletskaya, Anna, Bartle, Laura M., Salomon, Paulin, Wu, Rui, Maloney, Erin K., Kovtun, Yelena V., Ab, Olga, Lai, Kate, Chari, Ravi V. J., Widdison, Wayne C.
Gepubliceerd in ACS Med Chem Lett (2019)

Effect of Linker Stereochemistry on the Activity of Indolinobenzodiazepine Containing Antibody–Drug Conjugates (ADCs)

door Reid, Emily E., Archer, Katie E., Shizuka, Manami, Wilhelm, Alan, Yoder, Nicholas C., Bai, Chen, Fishkin, Nathan E., Harris, Luke, Maloney, Erin K., Salomon, Paulin, Hong, Erica, Wu, Rui, Ab, Olga, Jin, Shan, Lai, Katharine C., Sikka, Surina, Chari, Ravi V. J., Miller, Michael L.
Gepubliceerd in ACS Med Chem Lett (2019)

Synthesis and Evaluation of Camptothecin Antibody–Drug Conjugates

door Li, Wei, Veale, Karen H., Qiu, Qifeng, Sinkevicius, Kerstin W., Maloney, Erin K., Costoplus, Juliet A., Lau, Janet, Evans, Helen L., Setiady, Yulius, Ab, Olga, Abbott, Stephen M., Lee, Jenny, Wisitpitthaya, Somsinee, Skaletskaya, Anna, Wang, Lintao, Keating, Thomas A., Chari, Ravi V. J., Widdison, Wayne C.
Gepubliceerd in ACS Med Chem Lett (2019)