MBRS-19. BIOCHEMICAL AND ONCOGENIC CHARACTERIZATION OF HOTSPOT KBTBD4 MUTATIONS IN MEDULLOBLASTOMA

Por Muniz-Talavera, Hilmarie, Hadley, Jennifer, Northcott, Paul A
Publicado no Neuro Oncol (2018)

Medulloblastoma genomics in the modern molecular era

Por Kumar, Rahul, Liu, Anthony P. Y., Northcott, Paul A.
Publicado no Brain Pathol (2019)

Mouse models of medulloblastoma

Por Wu, Xiaochong, Northcott, Paul A., Croul, Sidney, Taylor, Michael D.
Publicado em 2011

Molecular subgroups of medulloblastoma

Por Northcott, Paul A, Dubuc, Adrian M, Pfister, Stefan, Taylor, Michael D
Publicado no Expert Rev Neurother (2012)

The Role of Chromatin Remodeling in Medulloblastoma

Por Jones, David T. W., Northcott, Paul A., Kool, Marcel, Pfister, Stefan M.
Publicado no Brain Pathol (2013)

Advances in classification of pediatric brain tumors through DNA methylation profiling: from research tool to frontline diagnostic

Por Kumar, Rahul, Liu, Anthony P.Y., Orr, Brent A., Northcott, Paul A., Robinson, Giles W.
Publicado no Cancer (2018)

Depletion of kinesin motor KIF20A to target cell fate control suppresses medulloblastoma tumour growth

Por Qiu, Runxiang, Wu, Jun, Gudenas, Brian, Northcott, Paul A., Wechsler-Reya, Robert J., Lu, Qiang
Publicado no Commun Biol (2021)

MOLECULAR (RE-)CLASSIFICATION OF CNS-PRIMITIVE NEUROECTODERMAL TUMORS

Por Kool, Marcel, Sturm, Dominik, Northcott, Paul A., Jones, David T.W., Korshunov, Andrey, Lichter, Peter, Pfister, Stefan
Publicado em 2014

TMOD-01 BCOR IS A NOVEL TUMOR SUPPRESSOR GENE IN SHH-DRIVEN MEDULLOBLASTOMA

Por Batora, Nadja V., Giese, Marcus, Sieber, Laura, Pfister, Stefan M., Bardwell, Vivian, Kawauchi, Daisuke, Northcott, Paul A.
Publicado no Neuro Oncol (2015)

STRUCTURAL VARIANTS SHUFFLE CHROMATIN TO ACTIVATE GFI1 FAMILY ONCOGENES IN MEDULLOBLASTOMA

Por Northcott, Paul A., Lee, Catherine, Zichner, Thomas, Lichter, Peter, Korbel, Jan O., Wechsler-Reya, Robert J., Pfister, Stefan M.
Publicado em 2014

PM-09 REGULATION OF MEDULLOBLASTOMA FORMATION BY Gfi1 AND Gfi1B

Por Lee, Catherine, Northcott, Paul A., Zichner, Thomas, Lichter, Peter, Korbel, Jan O., Pfister, Stefan M., Wechsler-Reya, Robert J.
Publicado em 2014

YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation

Por Fernandez-L, Africa, Northcott, Paul A., Dalton, James, Fraga, Charles, Ellison, David, Angers, Stephane, Taylor, Michael D., Kenney, Anna Marie
Publicado em 2009

Functional Genomics Identifies Drivers of Medulloblastoma Dissemination

Por Mumert, Michael, Dubuc, Adrian, Wu, Xiaochong, Northcott, Paul A., Chin, Steven S., Pedone, Carolyn A., Taylor, Michael D., Fults, Daniel W.
Publicado em 2012

Targeting the Enhancer of Zeste Homologue 2 in Medulloblastoma

Por Alimova, Irina, Venkataraman, Sujatha, Harris, Peter, Marquez, Victor E., Northcott, Paul A, Dubuc, Adrian, Taylor, Michael D, Foreman, Nicholas K, Vibhakar, Rajeev
Publicado em 2012

Deep Sequencing Identifies IDH1 R132S Mutation in Adult Medulloblastoma

Por Snuderl, Matija, Triscott, Joanna, Northcott, Paul A., Shih, Helen A., Kong, Esther, Robinson, Hayley, Dunn, Sandra E., Iafrate, A. John, Yip, Stephen
Publicado no J Clin Oncol (2015)

MBCL-42. SECOND GENERATION MOLECULAR SUBGROUPING OF MEDULLOBLASTOMA: TOWARDS A WORKING CONSENSUS OF GROUP 3/4 SUBTYPES

Por Sharma, Tanvi, Schwalbe, Edward C, Williamson, Daniel, Hovestadt, Volker, Chavez, Lukas, Kool, Marcel, Northcott, Paul A, Pfister, Stefan M, Clifford, Steven C
Publicado no Neuro Oncol (2018)

Tuberous sclerosis complex suppression in cerebellar development and medulloblastoma: separate regulation of mTOR activity and p27(Kip1) localization

Por Bhatia, Bobby, Northcott, Paul A., Hambardzumyan, Dolores, Govindarajan, Baskaran, Brat, Daniel J., Arbiser, Jack L., Holland, Eric C., Taylor, Michael D., Kenney, Anna Marie
Publicado em 2009

The WIP1 Oncogene Promotes Progression and Invasion of Aggressive Medulloblastoma Variants

Por Buss, Meghan C., Remke, Marc, Lee, Juhyun, Gandhi, Khanjan, Schniederjan, Matthew J., Kool, Marcel, Northcott, Paul A., Pfister, Stefan M., Taylor, Michael D., Castellino, Robert C.
Publicado no Oncogene (2014)

Bridging the treatment gap in infant medulloblastoma: molecularly informed outcomes of a globally feasible regimen

Por Baroni, Lorena V, Sampor, Claudia, Gonzalez, Adriana, Lubieniecki, Fabiana, Lamas, Gabriela, Rugilo, Carlos, Bartels, Ute, Heled, Ayala, Smith, Kyle S, Northcott, Paul A, Bouffet, Eric, Alderete, Daniel, Ramaswamy, Vijay
Publicado no Neuro Oncol (2020)

OTX2 is critical for the maintenance and progression of classic medulloblastoma

Por Adamson, David C., Shi, Qun, Wortham, Matthew, Northcott, Paul A., Di, Chunhui, Duncan, Christopher G., Li, Jianjun, McLendon, Roger E., Bigner, Darell D., Taylor, Michael D., Yan, Hai
Publicado em 2009