Choosing the optimal spectroscopic toolkit to understand protein function

Por Hough, Michael A.
Publicado no Biosci Rep (2017)

From crystal to structure with CCP4

Por Hough, Michael A., Wilson, Keith S.
Publicado no Acta Crystallogr D Struct Biol (2018)

Structural Evidence for a Copper-Bound Carbonate Intermediate in the Peroxidase and Dismutase Activities of Superoxide Dismutase

Por Strange, Richard W., Hough, Michael A., Antonyuk, Svetlana V., Hasnain, S. Samar
Publicado em 2012

Challenges and solutions for the analysis of in situ, in crystallo micro-spectrophotometric data

Por Dworkowski, Florian S. N., Hough, Michael A., Pompidor, Guillaume, Fuchs, Martin R.
Publicado no Acta Crystallogr D Biol Crystallogr (2015)

A QM/MM Study of Nitrite Binding Modes in a Three-Domain Heme-Cu Nitrite Reductase

Por Sen, Kakali, Hough, Michael A., Strange, Richard W., Yong, Chin W., Keal, Thomas W.
Publicado no Molecules (2018)

Response to Copper Stress in Streptomyces lividans Extends beyond Genes under Direct Control of a Copper-sensitive Operon Repressor Protein (CsoR)

Por Dwarakanath, Srivatsa, Chaplin, Amanda K., Hough, Michael A., Rigali, Sébastien, Vijgenboom, Erik, Worrall, Jonathan A. R.
Publicado em 2012

Serial crystallography captures enzyme catalysis in copper nitrite reductase at atomic resolution from one crystal

Por Horrell, Sam, Antonyuk, Svetlana V., Eady, Robert R., Hasnain, S. Samar, Hough, Michael A., Strange, Richard W.
Publicado no IUCrJ (2016)

Demonstration of Proton-coupled Electron Transfer in the Copper-containing Nitrite Reductases

Por Brenner, Sibylle, Heyes, Derren J., Hay, Sam, Hough, Michael A., Eady, Robert R., Hasnain, S. Samar, Scrutton, Nigel S.
Publicado em 2009

Modulation of ligand–heme reactivity by binding pocket residues demonstrated in cytochrome c' over the femtosecond–second temporal range

Por Russell, Henry J., Hardman, Samantha J. O., Heyes, Derren J., Hough, Michael A., Greetham, Gregory M., Towrie, Michael, Hay, Sam, Scrutton, Nigel S.
Publicado em 2013

Distinguishing Nitro vs Nitrito Coordination in Cytochrome c′ Using Vibrational Spectroscopy and Density Functional Theory

Por Nilsson, Zach N., Mandella, Brian L., Sen, Kakali, Kekilli, Demet, Hough, Michael A, Moenne-Loccoz, Pierre, Strange, Richard W., Andrew, Colin R.
Publicado no Inorg Chem (2017)

Heterogeneity in the Histidine-brace Copper Coordination Sphere in Auxiliary Activity Family 10 (AA10) Lytic Polysaccharide Monooxygenases

Por Chaplin, Amanda K., Wilson, Michael T., Hough, Michael A., Svistunenko, Dimitri A., Hemsworth, Glyn R., Walton, Paul H., Vijgenboom, Erik, Worrall, Jonathan A. R.
Publicado no J Biol Chem (2016)

Photoreduction and validation of haem–ligand intermediate states in protein crystals by in situ single-crystal spectroscopy and diffraction

Por Kekilli, Demet, Moreno-Chicano, Tadeo, Chaplin, Amanda K., Horrell, Sam, Dworkowski, Florian S. N., Worrall, Jonathan A. R., Strange, Richard W., Hough, Michael A.
Publicado no IUCrJ (2017)

Resolving polymorphs and radiation-driven effects in microcrystals using fixed-target serial synchrotron crystallography

Por Ebrahim, Ali, Appleby, Martin V., Axford, Danny, Beale, John, Moreno-Chicano, Tadeo, Sherrell, Darren A., Strange, Richard W., Hough, Michael A., Owen, Robin L.
Publicado no Acta Crystallogr D Struct Biol (2018)

One fold, two functions: cytochrome P460 and cytochrome c′-β from the methanotroph Methylococcus capsulatus (Bath)

Por Adams, Hannah R., Krewson, Callie, Vardanega, Jenny E., Fujii, Sotaro, Moreno, Tadeo, Chicano, Sambongi, Yoshihiro, Svistunenko, Dimitri, Paps, Jordi, Andrew, Colin R., Hough, Michael A.
Publicado no Chem Sci (2019)

Correction: One fold, two functions: cytochrome P460 and cytochrome c′-β from the methanotroph Methylococcus capsulatus (Bath)

Por Adams, Hannah R., Krewson, Callie, Vardanega, Jenny E., Fujii, Sotaro, Moreno-Chicano, Tadeo, Sambongi, Yoshihiro, Svistunenko, Dimitri, Paps, Jordi, Andrew, Colin R., Hough, Michael A.
Publicado no Chem Sci (2019)

Correction: One fold, two functions: cytochrome P460 and cytochrome c′-β from the methanotroph Methylococcus capsulatus (Bath)

Por Adams, Hannah R., Krewson, Callie, Vardanega, Jenny E., Fujii, Sotaro, Moreno-Chicano, Tadeo, Sambongi, Yoshihiro, Svistunenko, Dimitri, Paps, Jordi, Andrew, Colin R., Hough, Michael A.
Publicado no Chem Sci (2019)

Active-site protein dynamics and solvent accessibility in native Achromobacter cycloclastes copper nitrite reductase

Por Sen, Kakali, Horrell, Sam, Kekilli, Demet, Yong, Chin W., Keal, Thomas W., Atakisi, Hakan, Moreau, David W., Thorne, Robert E., Hough, Michael A., Strange, Richard W.
Publicado no IUCrJ (2017)

Structural consequences of the familial amyotrophic lateral sclerosis SOD1 mutant His46Arg

Por Antonyuk, Svetlana, Elam, Jennifer Stine, Hough, Michael A., Strange, Richard W., Doucette, Peter A., Rodriguez, Jorge A., Hayward, Lawrence J., Valentine, Joan Selverstone, Hart, P. John, Hasnain, S. Samar
Publicado em 2005

Successful sample preparation for serial crystallography experiments

Por Beale, John H., Bolton, Rachel, Marshall, Stephen A., Beale, Emma V., Carr, Stephen B., Ebrahim, Ali, Moreno-Chicano, Tadeo, Hough, Michael A., Worrall, Jonathan A. R., Tews, Ivo, Owen, Robin L.
Publicado no J Appl Crystallogr (2019)

Dimer destabilization in superoxide dismutase may result in disease-causing properties: Structures of motor neuron disease mutants

Por Hough, Michael A., Grossmann, J. Günter, Antonyuk, Svetlana V., Strange, Richard W., Doucette, Peter A., Rodriguez, Jorge A., Whitson, Lisa J., Hart, P. John, Hayward, Lawrence J., Valentine, Joan Selverstone, Hasnain, S. Samar
Publicado em 2004