Heterogeneity in the Histidine-brace Copper Coordination Sphere in Auxiliary Activity Family 10 (AA10) Lytic Polysaccharide Monooxygenases

Copper-dependent lytic polysaccharide monooxygenases (LPMOs) are enzymes that oxidatively deconstruct polysaccharides. The active site copper in LPMOs is coordinated by a histidine-brace. This utilizes the amino group and side chain of the N-terminal His residue with the side chain of a second His r...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Chaplin, Amanda K., Wilson, Michael T., Hough, Michael A., Svistunenko, Dimitri A., Hemsworth, Glyn R., Walton, Paul H., Vijgenboom, Erik, Worrall, Jonathan A. R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933455/
https://ncbi.nlm.nih.gov/pubmed/27129229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.722447
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