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Structural Evidence for a Copper-Bound Carbonate Intermediate in the Peroxidase and Dismutase Activities of Superoxide Dismutase

Copper-zinc superoxide dismutase (SOD) is of fundamental importance to our understanding of oxidative damage. Its primary function is catalysing the dismutation of superoxide to O(2) and H(2)O(2). SOD also reacts with H(2)O(2), leading to the formation of a strong copper-bound oxidant species that c...

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書誌詳細
主要な著者: Strange, Richard W., Hough, Michael A., Antonyuk, Svetlana V., Hasnain, S. Samar
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439438/
https://ncbi.nlm.nih.gov/pubmed/22984565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044811
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