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Structural Evidence for a Copper-Bound Carbonate Intermediate in the Peroxidase and Dismutase Activities of Superoxide Dismutase

Copper-zinc superoxide dismutase (SOD) is of fundamental importance to our understanding of oxidative damage. Its primary function is catalysing the dismutation of superoxide to O(2) and H(2)O(2). SOD also reacts with H(2)O(2), leading to the formation of a strong copper-bound oxidant species that c...

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Detalhes bibliográficos
Main Authors: Strange, Richard W., Hough, Michael A., Antonyuk, Svetlana V., Hasnain, S. Samar
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439438/
https://ncbi.nlm.nih.gov/pubmed/22984565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044811
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