The efficacy and safety of bevacizumab beyond first progression in patients treated with first-line mFOLFOX6 followed by second-line FOLFIRI in advanced colorectal cancer: a multicenter, single-arm, phase...

Por Nakayama, Goro, Uehara, Keisuke, Ishigure, Kiyoshi, Yokoyama, Hiroyuki, Ishiyama, Akiharu, Eguchi, Takehiko, Tsuboi, Kenji, Ohashi, Norifumi, Fujii, Tsutomu, Sugimoto, Hiroyuki, Koike, Masahiko, Fujiwara, Michitaka, Ando, Yuich, Kodera, Yasuhiro
Publicado em 2012

Fighting, loving, teaching an exploration of hope, armed love and critical urban pedagogies /

Por A. Daniels, Emily.
Publicado em 2012

Everolimus for Previously Treated Advanced Gastric Cancer: Results of the Randomized, Double-Blind, Phase III GRANITE-1 Study

Por Ohtsu, Atsushi, Ajani, Jaffer A., Bai, Yu-Xian, Bang, Yung-Jue, Chung, Hyun-Cheol, Pan, Hong-Ming, Sahmoud, Tarek, Shen, Lin, Yeh, Kun-Huei, Chin, Keisho, Muro, Kei, Kim, Yeul Hong, Ferry, David, Tebbutt, Niall C., Al-Batran, Salah-Eddin, Smith, Heind, Costantini, Chiara, Rizvi, Syed, Lebwohl, David, Van Cutsem, Eric
Publicado no J Clin Oncol (2013)

A phase I study of a novel potential intravaginal microbicide, PRO 2000, in healthy sexually inactive women

Por Van Damme, L., Wright, A., Depraetere, K., Rosenstein, I., Vandersmissen, V., Poulter, L., McKinlay, M., Van Dyck, E., Weber, J., Profy, A., Laga, M., Kitchen, V.
Publicado em 2000

A phase III, randomized, two-armed, double-blind, parallel, active controlled, and non-inferiority...

Por Jamshidi, Ahmadreza, Gharibdoost, Farhad, Vojdanian, Mahdi, Soroosh, Soosan G., Soroush, Mohsen, Ahmadzadeh, Arman, Nazarinia, Mohammad Ali, Mousavi, Mohammad, Karimzadeh, Hadi, Shakibi, Mohammad Reza, Rezaieyazdi, Zahra, Sahebari, Maryam, Hajiabbasi, Asghar, Ebrahimi, Ali Asghar, Mahjourian, Najmeh, Rashti, Amin Mohammadinejad
Publicado no Arthritis Res Ther (2017)

Pasireotide LAR maintains inhibition of GH and IGF-1 in patients with acromegaly for up to 25...

Por Sheppard, Michael, Bronstein, Marcello D., Freda, Pamela, Serri, Omar, De Marinis, Laura, Naves, Luciana, Rozhinskaya, Liudmila, Hermosillo Reséndiz, Karina, Ruffin, Matthieu, Chen, YinMiao, Colao, Annamaria
Publicado no Pituitary (2014)

A phase I pharmacokinetics study comparing PF-06439535 (a potential biosimilar) with bevacizumab in healthy male volunteers

Por Knight, Beverly, Rassam, Danielle, Liao, Shanmei, Ewesuedo, Reginald
Publicado no Cancer Chemother Pharmacol (2016)

24-MONTH ANALYSIS FROM PRIME, A PHASE 1B STUDY IN PATIENTS WITH PRODROMAL/MILD ALZHEIMER’S DISEASE

Por von Rosenstiel, P, Gheuens, S, O’Gorman, J, Chiao, P, Hock, C, Nitsch, R, Budd Haeberlein, S, Sandrock, A
Publicado no Innov Aging (2018)

Clinical pharmacodynamic/exposure characterisation of the multikinase inhibitor ilorasertib (ABT-348) in a phase 1 dose-escalation trial

Por Maitland, Michael L., Piha-Paul, Sarina, Falchook, Gerald, Kurzrock, Razelle, Nguyen, Ly, Janisch, Linda, Karovic, Sanja, McKee, Mark, Hoening, Elizabeth, Wong, Shekman, Munasinghe, Wijith, Palma, Joann, Donawho, Cherrie, Lian, Guinan K., Ansell, Peter, Ratain, Mark J., Hong, David
Publicado no Br J Cancer (2018)

Convection-enhanced delivery for diffuse intrinsic pontine glioma: a single-centre, dose-escalation, phase 1 trial

Por Souweidane, Mark M, Kramer, Kim, Pandit-Taskar, Neeta, Zhou, Zhiping, Haque, Sofia, Zanzonico, Pat, Carrasquillo, Jorge A, Lyashchenko, Serge K, Thakur, Sunitha B, Donzelli, Maria, Turner, Ryan S, Lewis, Jason S, Cheung, Nai-Kong V, Larson, Steven M, Dunkel, Ira J
Publicado no Lancet Oncol (2018)

A comparative phase 1 clinical trial to identify anti-infective mechanisms of vitamin D in people with HIV infection

Por Lachmann, Raskit, Bevan, Margaret A., Kim, Sangmi, Patel, Nishma, Hawrylowicz, Catherine, Vyakarnam, Annapurna, Peters, Barry S.
Publicado no AIDS (2015)

Lenalidomide in Nonmetastatic Biochemically Relapsed Prostate Cancer: Results of a Phase I/II Double-Blinded, Randomized Study

Por Keizman, Daniel, Zahurak, Marianna, Sinibaldi, Victoria, Carducci, Michael, Denmeade, Samuel, Drake, Charles, Pili, Roberto, Antonarakis, Emmanuel S., Hudock, Susan, Eisenberger, Mario
Publicado em 2010

Phase II studies to select the formulation of a multivalent HPV L1 virus-like particle (VLP) vaccine

Por Luxembourg, Alain, Brown, Darron, Bouchard, Celine, Giuliano, Anna R, Iversen, Ole-Erik, Joura, Elmar A, Penny, Mary E, Restrepo, Jaime A, Romaguera, Josefina, Maansson, Roger, Moeller, Erin, Ritter, Michael, Chen, Joshua
Publicado no Hum Vaccin Immunother (2015)

Pembrolizumab in combination with the oncolytic virus pelareorep and chemotherapy in patients with advanced pancreatic adenocarcinoma: a Phase 1b study

Por Mahalingam, Devalingam, Wilkinson, Grey A, Eng, Kevin H., Fields, Paul, Raber, Patrick, Moseley, Jennifer L., Cheetham, Karol, Coffey, Matt, Nuovo, Gerard, Kalinski, Pawel, Zhang, Bin, Arora, Sukeshi Patel, Fountzilas, Christos
Publicado no Clin Cancer Res (2019)

A phase 2 study of GVAX colon vaccine with cyclophosphamide and pembrolizumab in patients with mismatch repair proficient advanced colorectal cancer

Por Mark Yarchoan, Chiung‐Yu Huang, Qingfeng Zhu, Anna K. Ferguson, Jennifer N. Durham, Robert A. Anders, Elizabeth D. Thompson, Noah S. Rozich, Dwayne L. Thomas II, Julie M. Nauroth, Christina Rodriguez, Arsen Osipov, Ana De Jesus‐Acosta, Dung T. Le, Adrian G. Murphy, Daniel Laheru, Ross C. Donehower, Elizabeth M. Jaffee, Lei Zheng, Nilofer S. Azad
Publicado em 2020-02-01

A phase I/II study of gemcitabine during radiotherapy in children with newly diagnosed diffuse intrinsic pontine glioma

Por Veldhuijzen van Zanten, Sophie E. M., El-Khouly, Fatma E., Jansen, Marc H. A., Bakker, Dewi P., Sanchez Aliaga, Esther, Haasbeek, Cornelis J. A., Wolf, Nicole I., Zwaan, C. Michel, Vandertop, W. Peter, van Vuurden, Dannis G., Kaspers, Gertjan J. L.
Publicado no J Neurooncol (2017)

Phase I Study of CC-486 Alone and in Combination with Carboplatin or nab-Paclitaxel in Patients with Relapsed or Refractory Solid Tumors

Por Von Hoff, Daniel D., Rasco, Drew W., Heath, Elisabeth I., Munster, Pamela N., Schellens, Jan H.M., Isambert, Nicolas, Le Tourneau, Christophe, O’Neil, Bert, Mathijssen, Ron H.J., Lopez-Martin, Jose A., Edenfield, W. Jeff, Martin, Miguel, LoRusso, Patricia M., Bray, Gordon L., DiMartino, Jorge, Nguyen, Aaron, Liu, Kejian, Laille, Eric, Bendell, Johanna C.
Publicado no Clin Cancer Res (2018)

RTOG 0211: A Phase I/II Study of Radiation Therapy with Concurrent Gefitinib for Newly Diagnosed Glioblastoma Patients

Por Chakravarti, Arnab, Wang, Meihua, Robins, H. Ian, Lautenschlaeger, Tim, Curran, Walter J., Brachman, David G., Schultz, Christopher J., Choucair, Ali, Dolled-Filhart, Marisa, Christiansen, Jason, Gustavson, Mark, Molinaro, Annette, Mischel, Paul, Dicker, Adam P., Bredel, Markus, Mehta, Minesh
Publicado em 2012

A phase I/II trial of BNC105P with everolimus in metastatic renal cell carcinoma (mRCC)

Por Pal, Sumanta, Azad, Arun, Bhatia, Shailender, Drabkin, Harry, Costello, Brian, Sarantopoulos, John, Kanesvaran, Ravindran, Lauer, Richard, Starodub, Alexander, Hauke, Ralph, Sweeney, Christopher J., Hahn, Noah M., Sonpavde, Guru, Richey, Stephen, Breen, Timothy, Kremmidiotis, Gabriel, Leske, Annabell, Doolin, Elizabeth, Bibby, David C., Simpson, Jeremy, Iglesias, Jose, Hutson, Thomas
Publicado no Clin Cancer Res (2015)

Venetoclax plus R- or G-CHOP in non-Hodgkin lymphoma: results from the CAVALLI phase 1b trial

Por Zelenetz, Andrew D., Salles, Gilles, Mason, Kylie D., Casulo, Carla, Le Gouill, Steven, Sehn, Laurie H., Tilly, Herve, Cartron, Guillaume, Chamuleau, Martine E. D., Goy, Andre, Tam, Constantine S., Lugtenburg, Pieternella J., Petrich, Adam M., Sinha, Arijit, Samineni, Divya, Herter, Sylvia, Ingalla, Ellen, Szafer-Glusman, Edith, Klein, Christian, Sampath, Deepak, Kornacker, Martin, Mobasher, Mehrdad, Morschhauser, Franck
Publicado no Blood (2019)