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RTOG 0211: A Phase I/II Study of Radiation Therapy with Concurrent Gefitinib for Newly Diagnosed Glioblastoma Patients

PURPOSE: To determine the safety and efficacy of gefitinib, an EGFR tyrosine kinase inhibitor, in combination with radiation for newly diagnosed glioblastoma (GBM) patients. METHODS AND MATERIALS: Between 3/21/2002 and 5/03/2004 RTOG 0211 enrolled 31 and 147 GBM patients in the phase I and II arms r...

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Bibliographische Detailangaben
Hauptverfasser: Chakravarti, Arnab, Wang, Meihua, Robins, H. Ian, Lautenschlaeger, Tim, Curran, Walter J., Brachman, David G., Schultz, Christopher J., Choucair, Ali, Dolled-Filhart, Marisa, Christiansen, Jason, Gustavson, Mark, Molinaro, Annette, Mischel, Paul, Dicker, Adam P., Bredel, Markus, Mehta, Minesh
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199329/
https://ncbi.nlm.nih.gov/pubmed/23182702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2012.10.008
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