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A phase I pharmacokinetics study comparing PF-06439535 (a potential biosimilar) with bevacizumab in healthy male volunteers

PURPOSE: This study compared the pharmacokinetics of PF-06439535, a potential bevacizumab biosimilar, to bevacizumab sourced from the European Union (bevacizumab-EU) and USA (bevacizumab-US), and of bevacizumab-EU to bevacizumab-US. METHODS: In this double-blind study, 102 healthy males, aged 21–55 ...

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Detalhes bibliográficos
Publicado no:Cancer Chemother Pharmacol
Main Authors: Knight, Beverly, Rassam, Danielle, Liao, Shanmei, Ewesuedo, Reginald
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4819942/
https://ncbi.nlm.nih.gov/pubmed/26984210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-016-3001-2
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