Resultados da pesquisa - brain ((tumor ras) OR (tumour ras)) treat

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The Challenges and the Promise of Molecular Targeted Therapy in Malignant Gliomas()

Por Wang, Hongxiang, Xu, Tao, Jiang, Ying, Xu, Hanchong, Yan, Yong, Fu, Da, Chen, Juxiang
Publicado no Neoplasia (2015)

“...Malignant gliomas are the most common malignant primary brain tumors and one of the most...”
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TNF-α receptor 1 knockdown in the subfornical organ ameliorates sympathetic excitation and cardiac hemodynamics in heart failure rats

Por Yu, Yang, Wei, Shun-Guang, Weiss, Robert M., Felder, Robert B.
Publicado no Am J Physiol Heart Circ Physiol (2017)

“... and renin-angiotensin system (RAS) activity in cardiovascular regions of the brain, contributing...”
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Microglial Activation Is Modulated by Captopril: in Vitro and in Vivo Studies

Por Keren Asraf, Nofar Torika, Ron N. Apte, Sigal Fleisher-Berkovich
Publicado em 2018-05-01

“...The renin-angiotensin system (RAS) is an important peripheral system involved in homeostasis...”
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Microglial Activation Is Modulated by Captopril: in Vitro and in Vivo Studies

Por Asraf, Keren, Torika, Nofar, Apte, Ron N., Fleisher-Berkovich, Sigal
Publicado no Front Cell Neurosci (2018)

“...The renin-angiotensin system (RAS) is an important peripheral system involved in homeostasis...”
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EXTH-22. VERTEPORFIN TREATMENT INHIBITS GBM GROWTH AND MIGRATION AND INFORMS HIPPO/RTK CROSSTALK

Por Barrette, Anne Marie, Tome-Garcia, Jessica, Zaware, Nilesh, Zhou, Ming-Ming, Birtwistle, Marc, Tsankova, Nadejda
Publicado no Neuro Oncol (2018)

“.... Notably, VP penetrated into the brain parenchyma, and resulted in lower tumor burden without systemic...”
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PA01.13. Hemiplegia - An ayurvedic perspective

Por Hariharan, Subramanian, Prasanna Kumar, T. M., Gobinath, N.
Publicado em 2012

“... etiologies like Systemic Hypertension, Injuries, Tumors, Embolism and other vascular occlusions of the brain...”
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CSIG-06. THE MOLECULAR SUBTYPE OF PRIMARY GLIOBLASTOMA CELLS CORRELATES WITH RESPONSE TO THERAPEUTIC AGENTS THAT INDUCE APOPTOSIS OR SENESCENCE

Por Kumar, Ritesh, Lorimer, Ian
Publicado no Neuro Oncol (2018)

“...INTRODUCTION: Glioblastoma (GBM) is the most common adult primary brain tumour. Despite maximal...”
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CSIG-39. Fyn, AN ONCOGENE THAT REDUCES GLIOBLASTOMA SURVIVAL YET SENSITIZES TO CHEMO-RADIOTHERAPY

Por Comba, Andrea, Kadiyala, Padma, Argento, Anna E, Patel, Priti, Nunez, Felipe J, Saxena, Meghna, Castro, Maria G, Lowenstein, Pedro R
Publicado no Neuro Oncol (2017)

“... in malignant brain tumors (GBM) remains contradictory. Bioinformatics network analysis of the transcriptome...”
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Drug-Carrying Capacity and Anticancer Effect of the Folic Acid- and Berberine-Loaded Silver Nanomaterial To Regulate the AKT-ERK Pathway in Breast Cancer

Por Bhanumathi, Ramasamy, Manivannan, Manickam, Thangaraj, Ramasundaram, Kannan, Soundarapandian
Publicado no ACS Omega (2018)

“...[Image: see text] Currently, in clinics, breast cancer is treated with free chemotherapeutic drugs...”
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Upregulation of PTEN in Glioma Cells by Cord Blood Mesenchymal Stem Cells Inhibits Migration via Downregulation of the PI3K/Akt Pathway

Por Dasari, Venkata Ramesh, Kaur, Kiranpreet, Velpula, Kiran Kumar, Gujrati, Meena, Fassett, Daniel, Klopfenstein, Jeffrey D., Dinh, Dzung H., Rao, Jasti S.
Publicado em 2010

“... are responsible for the inhibition of tumor growth in the mouse brain. CONCLUSIONS/SIGNIFICANCE: Our studies...”
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Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cells

Por Abouantoun, Thamara J., Castellino, Robert C., MacDonald, Tobey J.
Publicado em 2010

“..., particularly given evidence of its ability to cross the blood–brain barrier to target tumor cells, and thus...”
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Adherence to Antiemetic Guidelines in Patients with Malignant Glioma: A Quality Improvement Project to Translate Evidence into Practice

Por Affronti, Mary Lou, Schneider, Susan M., Herndon, James E., Schlundt, Susan, Friedman, Henry S.
Publicado no Support Care Cancer (2014)

“... impair cancer patients’ quality of life (QOL). Review of Duke University Preston Robert Tisch Brain Tumor...”
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TMOD-17. A NOVEL ADENOVIRAL-PERMISSIVE, IMMUNOCOMPETENT HAMSTER MODEL TO EVALUATE ONCOLYTIC ADENOVIRAL THERAPY FOR GLIOBLASTOMA

Por Phillips, Lynette, Li, Shoudong, Gumin, Joy, Ledbetter, Daniel, Hossain, Anwar, Kerrigan, Brittany, Gomez-Manzano, Candelaria, Fueyo, Juan, Lang, Frederick
Publicado no Neuro Oncol (2018)

“... T antigen, and h-RasV12 and re-implanted the transformed cells into hamster brains where they developed...”
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AT-48 A PHASE 1 TRIAL OF CARBOXYAMIDOTRIAZOLE OROTATE (CTO) IN COMBINATION WITH BEVACIZUMAB FOR ADULT PATIENTS WITH RECURRENT MALIGNANT GLIOMA POST-BEVACIZUMAB FAILURE

Por Ranjan, Tulika, Peters, katherine B., Vlahovic, Gordana, Watts, Jason, Dutton, Shelley, Boulton, Susan, Lipp, Eric, Herndon, James, Healy, Patrick, Miller, Elizabeth, Friedman, Henry, Karmali, Rashida, Desjardins, Annick
Publicado em 2014

“..., including EGFR, MEK, RAS, HDAC, HSP90, WNT/B-catenin, Akt, ERK, VEGF and Bcr-Abl. A recent Phase I safety...”
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Protection of nigral dopaminergic neurons by AAV1 transduction with Rheb(S16H) against neurotoxic inflammation in vivo

Por Kim, Sehwan, Moon, Gyeong Joon, Oh, Yong-Seok, Park, Jungha, Shin, Won-Ho, Jeong, Jae Yeong, Choi, Kwang Shik, Jin, Byung Kwan, Kholodilov, Nikolai, Burke, Robert E, Kim, Hyung-Jun, Ha, Chang Man, Lee, Seok-Geun, Kim, Sang Ryong
Publicado no Exp Mol Med (2018)

“... dopaminergic (DA) neurons with constitutively active ras homolog enriched in brain with a mutation of serine...”
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Isolated central nervous system progression on Crizotinib: An Achilles heel of non-small cell lung cancer with EML4-ALK translocation?

Por Chun, Stephen G., Choe, Kevin S., Iyengar, Puneeth, Yordy, John S., Timmerman, Robert D.
Publicado em 2012

“... survival despite efforts to target specific oncogenic addiction pathways that may drive these tumors...”
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Paradoxical activation and RAF inhibitor resistance of BRAF protein kinase fusions characterizing pediatric astrocytomas

Por Sievert, Angela J., Lang, Shih-Shan, Boucher, Katie L., Madsen, Peter J., Slaunwhite, Erin, Choudhari, Namrata, Kellet, Meghan, Storm, Phillip B., Resnick, Adam C.
Publicado em 2013

“...Astrocytomas are the most common type of brain tumors in children. Activated BRAF protein kinase...”
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Poster Session B

Publicado no Mol Cell Proteomics (2017)

“... on medulloblastoma, the most common malignant pediatric brain tumor, here we have generated integrated omic data sets...”
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