CSIG-39. Fyn, AN ONCOGENE THAT REDUCES GLIOBLASTOMA SURVIVAL YET SENSITIZES TO CHEMO-RADIOTHERAPY

Fyn, a Src family kinase member (SFK), has oncogenic activities. However, the function of Fyn in malignant brain tumors (GBM) remains contradictory. Bioinformatics network analysis of the transcriptome of GBM neurospheres suggested that Fyn is a highly connected node. Thus, Fyn was selected as a pot...

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Publié dans:Neuro Oncol
Auteurs principaux: Comba, Andrea, Kadiyala, Padma, Argento, Anna E, Patel, Priti, Nunez, Felipe J, Saxena, Meghna, Castro, Maria G, Lowenstein, Pedro R
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2017
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693107/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.233
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