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TMIC-62. FYN, AN EFFECTOR OF ONCOGENIC RECEPTOR TYROSINE KINASES SIGNALING IN GLIOBLASTOMA, INHIBITS ANTI-GLIOMA IMMUNE RESPONSES: IMPLICATIONS FOR IMMUNOTHERAPY

There is currently much excitement for the use of immunotherapies in cancer. In spite of positive results using checkpoint inhibitors in melanoma and CAR T cells in leukemias, these strategies have not yet achieved robust clinical responses in human gliomas. A powerful inhibitory microenvironment is...

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Détails bibliographiques
Publié dans:Neuro Oncol
Auteurs principaux: Comba, Andrea, J Dunn, Patrick, E Argento, Anna, Kadiyala, Padma, Ventosa, Maria, Patel, Priti, Zamler, Daniel, Nunez, Felipe, Zhao, Lili, Castro, Maria, Lowenstein, Pedro
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6845626/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.1096
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