CSIG-07. COMPARATIVE RNA-SEQ ANALYSIS OF GLIOMAS OF DIFFERENT MALIGNANCY IDENTIFIES FYN AS A NOVEL REGULATOR OF GBM AGGRESSIVENESS

Glioblastomas (GBM) are the most frequent and aggressive primary tumors of the brain. Fyn, a Src family kinase member, is overexpressed in human GBM. Its function, however, remains poorly understood. We analyzed the differential gene expression (DE) of highly malignant tumor (NPA: N-Ras/shp53/shATRx...

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Publicado no:Neuro Oncol
Main Authors: Comba, Andrea, Kadiyala, Padma, Dunn, Patrick, Argento, Anna, Patel, Priti, Alghamri, Mahmoud, Nunez, Felipe, G Castro, Maria, Lowenstein, Pedro
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216567/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.173
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