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Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cells

We previously showed that inhibition of the platelet-derived growth factor receptor (PDGFR) blocks the survival and migration of medulloblastoma cells. Identification of in vitro PDGFR-targeting pharmacologic agents that are suitable for preclinical testing in medulloblastoma models in vivo will be...

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Detalhes bibliográficos
Main Authors: Abouantoun, Thamara J., Castellino, Robert C., MacDonald, Tobey J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997175/
https://ncbi.nlm.nih.gov/pubmed/20524040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-010-0259-9
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