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The rationale for targeted therapies in medulloblastoma

Medulloblastoma (MB) is the most frequent malignant brain tumor in children. Patients with MB who are classified as having high-risk disease or those with recurrent disease respond poorly to current therapies and have an increased risk of MB-related mortality. Preclinical studies and molecular profi...

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Detalhes bibliográficos
Main Authors: MacDonald, Tobey J., Aguilera, Dolly, Castellino, Robert C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870836/
https://ncbi.nlm.nih.gov/pubmed/24305711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/not147
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