Long-term safety and activity of axicabtagene ciloleucel in refractory large B-cell lymphoma (ZUMA-1): a single-arm, multicentre, phase 1-2 trial

Por Locke, Frederick L, Ghobadi, Armin, Jacobson, Caron A, Miklos, David B, Lekakis, Lazaros J, Oluwole, Olalekan O, Lin, Yi, Braunschweig, Ira, Hill, Brian T, Timmerman, John M, Deol, Abhinav, Reagan, Patrick M, Stiff, Patrick, Flinn, Ian W, Farooq, Umar, Goy, Andre, McSweeney, Peter A, Munoz, Javier, Siddiqi, Tanya, Chavez, Julio C, Herrera, Alex F, Bartlett, Nancy L, Wiezorek, Jeffrey S, Navale, Lynn, Xue, Allen, Jiang, Yizhou, Bot, Adrian, Rossi, John M, Kim, Jenny J, Go, William Y, Neelapu, Sattva S
Publicado no Lancet Oncol (2018)

Bivalent oral cholera vaccine in participants aged 1 year and older in the Dominican Republic: A phase III, single-arm, safety and immunogenicity trial

Por Cordero De Los Santos, Lina, Feris-Iglesias, Jesús, Aloysia D'Cor, Naveena, Midde, Venkata Jayanth, Patnaik, Badri Narayan, Thollot, Yaël, Rasuli, Anvar, Desauziers, Eric
Publicado no Hum Vaccin Immunother (2018)

A phase 1, open-label, single-arm study evaluating the ocular safety of OTX-101 and systemic absorption of cyclosporine in healthy human volunteers

Por Karpecki, Paul M, Weiss, Sidney L, Kramer, William G, O’Connor, Patrick, Evans, David, Johnston, Josh, Jasper, April L, Justice, Angela, Ogundele, Abayomi B, Devries, Doug
Publicado no Clin Ophthalmol (2019)

Many-to-one comparisons after safety selection in multi-arm clinical trials

Por Hlavin, Gerald, Hampson, Lisa V., Koenig, Franz
Publicado no PLoS One (2017)

Phase 1 safety assessment of intrathecal oxytocin

Por Eisenach, James C., Tong, Chuanyao, Curry, Regina
Publicado no Anesthesiology (2015)

Safety and feasibility of third-party multipotent adult progenitor cells for immunomodulation therapy after liver transplantation--a phase I study (MISOT-I)

Por Popp, Felix C, Fillenberg, Barbara, Eggenhofer, Elke, Renner, Philipp, Dillmann, Johannes, Benseler, Volker, Schnitzbauer, Andreas A, Hutchinson, James, Deans, Robert, Ladenheim, Deborah, Graveen, Cheryl A, Zeman, Florian, Koller, Michael, Hoogduijn, Martin J, Geissler, Edward K, Schlitt, Hans J, Dahlke, Marc H
Publicado em 2011

Regorafenib in Japanese patients with solid tumors: phase I study of safety, efficacy, and pharmacokinetics

Por Sunakawa, Yu, Furuse, Junji, Okusaka, Takuji, Ikeda, Masafumi, Nagashima, Fumio, Ueno, Hideki, Mitsunaga, Shuichi, Hashizume, Kensei, Ito, Yuichiro, Sasaki, Yasutsuna
Publicado em 2013

Safety and Tolerability of CSL112, a Reconstituted, Infusible, Plasma-Derived Apolipoprotein A-I...

Por Michael Gibson, C., Korjian, Serge, Tricoci, Pierluigi, Daaboul, Yazan, Yee, Megan, Jain, Purva, Alexander, John H., Steg, P. Gabriel, Lincoff, A. Michael, Kastelein, John J.P., Mehran, Roxana, D’Andrea, Denise M., Deckelbaum, Lawrence I., Merkely, Bela, Zarebinski, Maciej, Ophuis, Ton Oude, Harrington, Robert A.
Publicado no Circulation (2016)

A single arm phase 1b study of everolimus and sunitinib in patients with advanced renal cell carcinoma (RCC)

Por Kanesvaran, R., Watt, K., Turnbull, J. D., Armstrong, A. J., Cohen-Wolkowiez, M., George, D. J.
Publicado no Clin Genitourin Cancer (2014)

Nab-paclitaxel plus S-1 as first-line followed by S-1 maintenance for advanced pancreatic adenocarcinoma: a single-arm phase II trial

Por Zhang, Wen, Du, Chunxia, Sun, Yongkun, Yang, Lin, Cui, Chengxu, Jiang, Zhichao, Wang, Chengfeng, Wang, Jinwang, Zhou, Aiping
Publicado no Cancer Chemother Pharmacol (2018)

Safety and immunogenicity of the killed bivalent (O1 and O139) whole-cell cholera vaccine in the Philippines

Por Capeding, Maria Rosario Z., Gonzales, Maria Liza Antoinette M., Dhingra, Mandeep Singh, D'Cor, Naveena Aloysia, Midde, Venkat Jayanth, Patnaik, Badri Narayan, Thollot, Yaël, Desauziers, Eric
Publicado no Hum Vaccin Immunother (2017)

Efficacy and Safety of High-Specific-Activity (131)I-MIBG Therapy in Patients with Advanced Pheochromocytoma or Paraganglioma

Por Pryma, Daniel A., Chin, Bennett B., Noto, Richard B., Dillon, Joseph S., Perkins, Stephanie, Solnes, Lilja, Kostakoglu, Lale, Serafini, Aldo N., Pampaloni, Miguel H., Jensen, Jessica, Armor, Thomas, Lin, Tess, White, Theresa, Stambler, Nancy, Apfel, Stuart, DiPippo, Vincent A., Mahmood, Syed, Wong, Vivien, Jimenez, Camilo
Publicado no J Nucl Med (2019)

Efficacy and safety of maraviroc vs. efavirenz in treatment-naive patients with HIV-1: 5-year findings

Por Cooper, David A., Heera, Jayvant, Ive, Prudence, Botes, Mariette, Dejesus, Edwin, Burnside, Robert, Clumeck, Nathan, Walmsley, Sharon, Lazzarin, Adriano, Mukwaya, Geoffrey, Saag, Michael, van Der Ryst, Elna
Publicado em 2014

Heat shock protein peptide complex-96 vaccination for newly diagnosed glioblastoma: a phase I, single-arm trial

Por Ji, Nan, Zhang, Yang, Liu, Yunpeng, Xie, Jian, Wang, Yi, Hao, Shuyu, Gao, Zhixian
Publicado no JCI Insight (2018)

A Phase I Study to Assess the Feasibility and Oncologic Safety of Axillary Reverse Mapping in Breast Cancer Patients

Por Bedrosian, Isabelle, Babiera, Gildy V., Mittendorf, Elizabeth A., Kuerer, Henry M., Pantoja, Laura, Hunt, Kelly K., Krishnamurthy, Savitri, Meric-Bernstam, Funda
Publicado no Cancer (2010)

Efficacy and Safety of 12-week Interferon-based Danoprevir Regimen in Patients with Genotype 1 Chronic Hepatitis C

Por Wei, Lai, Shang, Jia, Ma, Yuanji, Xu, Xiaoyuan, Huang, Yan, Guan, Yujuan, Duan, Zhongping, Zhang, Wenhong, Gao, Zhiliang, Zhang, Mingxiang, Li, Jun, Jia, Jidong, Yang, Yongfeng, Wen, Xiaofeng, Wang, Maorong, Jia, Zhansheng, Ning, Bo, Chen, Yongping, Qi, Yue, Du, Jie, Jiang, Jianning, Tong, Lixin, Xie, Yao, Wu, Jinzi J.
Publicado no J Clin Transl Hepatol (2019)

Phase 1 Safety, Pharmacokinetics, and Pharmacodynamics of Dapivirine and Maraviroc Vaginal Rings: a Double-Blind Randomized Trial

Por Chen, Beatrice A., Panther, Lori, Marzinke, Mark A., Hendrix, Craig W., Hoesley, Craig J., van der Straten, Ariane, Husnik, Marla J., Soto-Torres, Lydia, Nel, Annalene, Johnson, Sherri, Richardson-Harman, Nicola, Rabe, Lorna K., Dezzutti, Charlene S.
Publicado no J Acquir Immune Defic Syndr (2015)

An open-label, single-arm, phase I/II study of lower-dose decitabine based therapy in patients with advanced hepatocellular carcinoma

Por Mei, Qian, Chen, Meixia, Lu, Xuechun, Li, Xiang, Duan, Feng, Wang, Maoqiang, Luo, Guangbin, Han, Weidong
Publicado no Oncotarget (2015)

Safety and tolerability of topically administered autologous, apoptotic PBMC secretome (APOSEC) in dermal wounds: a randomized Phase 1 trial (MARSYAS I)

Por Simader, Elisabeth, Traxler, Denise, Kasiri, Mohammad Mahdi, Hofbauer, Helmut, Wolzt, Michael, Glogner, Christoph, Storka, Angela, Mildner, Michael, Gouya, Ghazaleh, Geusau, Alexandra, Fuchs, Carola, Eder, Claudia, Graf, Alexandra, Schaden, Michaela, Golabi, Bahar, Aretin, Marie-Bernadette, Suessner, Susanne, Gabriel, Christian, Klepetko, Walter, Tschachler, Erwin, Ankersmit, Hendrik Jan
Publicado no Sci Rep (2017)

... FAME‐04: A Phase 1 trial to assess the safety, acceptability, pharmacokinetics...

Por Bunge, Katherine E, Dezzutti, Charlene S, Hendrix, Craig W, Marzinke, Mark A, Spiegel, Hans M L, Moncla, Bernard J, Schwartz, Jill L, Meyn, Leslie A, Richardson‐Harman, Nicola, Rohan, Lisa C, Hillier, Sharon L
Publicado no J Int AIDS Soc (2018)