Safety and tolerability of topically administered autologous, apoptotic PBMC secretome (APOSEC) in dermal wounds: a randomized Phase 1 trial (MARSYAS I)

Developing effective therapies against chronic wound healing deficiencies is a global priority. Thus we evaluated the safety of two different doses of topically administered autologous APOSEC, the secretome of apoptotic peripheral blood mononuclear cells (PBMCs), in healthy male volunteers with arti...

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Publicado no:Sci Rep
Main Authors: Simader, Elisabeth, Traxler, Denise, Kasiri, Mohammad Mahdi, Hofbauer, Helmut, Wolzt, Michael, Glogner, Christoph, Storka, Angela, Mildner, Michael, Gouya, Ghazaleh, Geusau, Alexandra, Fuchs, Carola, Eder, Claudia, Graf, Alexandra, Schaden, Michaela, Golabi, Bahar, Aretin, Marie-Bernadette, Suessner, Susanne, Gabriel, Christian, Klepetko, Walter, Tschachler, Erwin, Ankersmit, Hendrik Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524970/
https://ncbi.nlm.nih.gov/pubmed/28740204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06223-x
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