E. coli Endotoxin Modulates the Expression of Sirtuin Proteins in PBMC in Humans

Background. Sirtuin (SIRT) proteins are class I histone deacetylases displaying gene regulatory functions in inflammatory, cancer, and metabolic diseases. These SIRT actions involve the nuclear factor κB and its inhibitor IκB pathway. However, the regulation of SIRT in vivo is still unclear. Materia...

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Main Authors: Storka, Angela, Führlinger, Gerhard, Seper, Martin, Wang, Lisa, Jew, Michael, Leisser, Asha, Wolzt, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3852091/
https://ncbi.nlm.nih.gov/pubmed/24347837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/876943
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