E. coli Endotoxin Modulates the Expression of Sirtuin Proteins in PBMC in Humans

Background. Sirtuin (SIRT) proteins are class I histone deacetylases displaying gene regulatory functions in inflammatory, cancer, and metabolic diseases. These SIRT actions involve the nuclear factor κB and its inhibitor IκB pathway. However, the regulation of SIRT in vivo is still unclear. Materia...

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Main Authors: Storka, Angela, Führlinger, Gerhard, Seper, Martin, Wang, Lisa, Jew, Michael, Leisser, Asha, Wolzt, Michael
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3852091/
https://ncbi.nlm.nih.gov/pubmed/24347837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/876943
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