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Human Pharmacokinetics of High Dose Oral Curcumin and Its Effect on Heme Oxygenase-1 Expression in Healthy Male Subjects

Purpose. Heme oxygenase-1 (HO-1) has been proposed to exert pharmacological benefits by its antioxidative and anti-inflammatory effects. HO-1 expression may be affected by the GT length polymorphism in the promoter region of the HO-1 gene. We investigated the inducibility of HO-1 by orally administe...

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Detalhes bibliográficos
Main Authors: Klickovic, Uros, Doberer, Daniel, Gouya, Ghazaleh, Aschauer, Stefan, Weisshaar, Stefan, Storka, Angela, Bilban, Martin, Wolzt, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3925623/
https://ncbi.nlm.nih.gov/pubmed/24592391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/458592
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