Long-term safety and activity of axicabtagene ciloleucel in refractory large B-cell lymphoma (ZUMA-1): a single-arm, multicentre, phase 1-2 trial

Por Locke, Frederick L, Ghobadi, Armin, Jacobson, Caron A, Miklos, David B, Lekakis, Lazaros J, Oluwole, Olalekan O, Lin, Yi, Braunschweig, Ira, Hill, Brian T, Timmerman, John M, Deol, Abhinav, Reagan, Patrick M, Stiff, Patrick, Flinn, Ian W, Farooq, Umar, Goy, Andre, McSweeney, Peter A, Munoz, Javier, Siddiqi, Tanya, Chavez, Julio C, Herrera, Alex F, Bartlett, Nancy L, Wiezorek, Jeffrey S, Navale, Lynn, Xue, Allen, Jiang, Yizhou, Bot, Adrian, Rossi, John M, Kim, Jenny J, Go, William Y, Neelapu, Sattva S
Publicado no Lancet Oncol (2018)

Bivalent oral cholera vaccine in participants aged 1 year and older in the Dominican Republic: A phase III, single-arm, safety and immunogenicity trial

Por Cordero De Los Santos, Lina, Feris-Iglesias, Jesús, Aloysia D'Cor, Naveena, Midde, Venkata Jayanth, Patnaik, Badri Narayan, Thollot, Yaël, Rasuli, Anvar, Desauziers, Eric
Publicado no Hum Vaccin Immunother (2018)

A phase 1, open-label, single-arm study evaluating the ocular safety of OTX-101 and systemic absorption of cyclosporine in healthy human volunteers

Por Karpecki, Paul M, Weiss, Sidney L, Kramer, William G, O’Connor, Patrick, Evans, David, Johnston, Josh, Jasper, April L, Justice, Angela, Ogundele, Abayomi B, Devries, Doug
Publicado no Clin Ophthalmol (2019)

A single arm phase 1b study of everolimus and sunitinib in patients with advanced renal cell carcinoma (RCC)

Por Kanesvaran, R., Watt, K., Turnbull, J. D., Armstrong, A. J., Cohen-Wolkowiez, M., George, D. J.
Publicado no Clin Genitourin Cancer (2014)

Nab-paclitaxel plus S-1 as first-line followed by S-1 maintenance for advanced pancreatic adenocarcinoma: a single-arm phase II trial

Por Zhang, Wen, Du, Chunxia, Sun, Yongkun, Yang, Lin, Cui, Chengxu, Jiang, Zhichao, Wang, Chengfeng, Wang, Jinwang, Zhou, Aiping
Publicado no Cancer Chemother Pharmacol (2018)

Heat shock protein peptide complex-96 vaccination for newly diagnosed glioblastoma: a phase I, single-arm trial

Por Ji, Nan, Zhang, Yang, Liu, Yunpeng, Xie, Jian, Wang, Yi, Hao, Shuyu, Gao, Zhixian
Publicado no JCI Insight (2018)

An open-label, single-arm, phase I/II study of lower-dose decitabine based therapy in patients with advanced hepatocellular carcinoma

Por Mei, Qian, Chen, Meixia, Lu, Xuechun, Li, Xiang, Duan, Feng, Wang, Maoqiang, Luo, Guangbin, Han, Weidong
Publicado no Oncotarget (2015)

A phase 2, single-arm study of an autologous dendritic cell treatment against mucin 1 in patients with advanced epithelial ovarian cancer

Por Mitchell, Paul LR, Quinn, Michael A, Grant, Peter T, Allen, David G, Jobling, Thomas W, White, Shane C, Zhao, Anne, Karanikas, Vaios, Vaughan, Hilary, Pietersz, Geoffrey, McKenzie, Ian FC, Gargosky, Sharron E, Loveland, Bruce E
Publicado em 2014

Combination TS‐1 plus EGFR‐tyrosine kinase inhibitors (TKIs) for the treatment of non‐small cell lung cancer after progression on first‐line or further EGFR‐TKIs: A phase II, single‐arm trial

Por Yang, Lu, Yang, Sheng, Liu, Yutao, Li, Junling, Hu, Xingsheng, Wang, Yalei, Zhang, Yan, Wang, Yan
Publicado no Thorac Cancer (2018)

A single-arm phase II trial of combined chemotherapy with S-1, oral leucovorin, and bevacizumab...

Por Yamaguchi, Kazuhisa, Taniguchi, Hiroya, Komori, Azusa, Narita, Yukiya, Nitta, Sohei, Nomura, Motoo, Kadowaki, Shigenori, Takahari, Daisuke, Ura, Takashi, Andoh, Masashi, Muro, Kei, Mori, Keita, Igarashi, Yoshinori
Publicado no BMC Cancer (2015)

Sirolimus in patients with clinically active systemic lupus erythematosus resistant to, or intolerant of, conventional medications: a single-arm, open-label, phase 1/2 trial

Por Lai, Zhi-Wei, Kelly, Ryan, Winans, Thomas, Marchena, Ivan, Shadakshari, Ashwini, Yu, Julie, Dawood, Maha, Garcia, Ricardo, Tily, Hajra, Francis, Lisa, Faraone, Stephen V, Phillips, Paul E, Perl, Andras
Publicado no Lancet (2018)

Imatinib mesylate (Gleevec) in the treatment of diffuse cutaneous systemic sclerosis: results of a 1-year, phase IIa, single-arm, open-label clinical trial

Por Spiera, Robert F, Gordon, Jessica K, Mersten, Jamie N, Magro, Cynthia M, Mehta, Mansi, Wildman, Horatio F, Kloiber, Stacey, Kirou, Kyriakos A, Lyman, Stephen, Crow, Mary K
Publicado em 2011

Combination of the histone deacetylase inhibitor vorinostat with bevacizumab in patients with clear-cell renal cell carcinoma: a multicentre, single-arm phase I/II clinical trial

Por Pili, Roberto, Liu, Glenn, Chintala, Sreenivasulu, Verheul, Hendrick, Rehman, Shabnam, Attwood, Kristopher, Lodge, Martin A, Wahl, Richard, Martin, James I, Miles, Kiersten Marie, Paesante, Silvia, Adelaiye, Remi, Godoy, Alejandro, King, Serina, Zwiebel, James, Carducci, Michael A
Publicado no Br J Cancer (2017)

ATIM-05. A PHASE I STUDY TARGETING NEWLY DIAGNOSED GLIOBLASTOMA WITH ANTI-CD3 × ANTI-EGFR...

Por Fadul, Camilo, Kim, Jungeun, Thakur, Archana, Purow, Benjamin, Lopes, Maria-Beatriz, Schiff, David, Kassay-McAllister, Jessica, Donahue, Joseph, Liu, Qin, Lum, Lawrence
Publicado no Neuro Oncol (2019)

Many-to-one comparisons after safety selection in multi-arm clinical trials

Por Hlavin, Gerald, Hampson, Lisa V., Koenig, Franz
Publicado no PLoS One (2017)

Adjuvant Alpha-Fetoprotein-Derived Peptide After Transarterial Chemoembolization in Patients With Hepatocellular Carcinoma: Protocol for a Safety Study

Por Nomura, Akihiro, Terashima, Takeshi, Mizukoshi, Eishiro, Kitahara, Masaaki, Murayama, Toshinori, Kaneko, Shuichi
Publicado no JMIR Res Protoc (2020)

Update on the Cardiac Safety of Moxifloxacin

Por Haverkamp, Wilhelm, Kruesmann, Frank, Fritsch, Anna, van Veenhuyzen, David, Arvis, Pierre
Publicado em 2012

Tocilizumab efficacy and safety in rheumatoid arthritis patients after inadequate response...

Por Abdulkader, Omer Ahmad Fatheddin, Qushmaq, Khalid, Aljishi, Faiza
Publicado no Ann Saudi Med (2016)

Randomized Phase III Study to Assess Efficacy and Safety of Adjuvant CAPOX with or without...

Por Snoeren, Nikol, van Hillegersberg, Richard, Schouten, Sander B., Bergman, Andre M., van Werkhoven, Erikv, Dalesio, Otilia, Tollenaar, Rob A.E.M., Verheul, Henk M., van der Sijp, Joost, Borel Rinkes, Inne H.M., Voest, E.E.
Publicado no Neoplasia (2017)

Efficacy and Safety of Trabectedin or Dacarbazine for Metastatic Liposarcoma or Leiomyosarcoma After Failure of Conventional Chemotherapy: Results of a Phase III Randomized Multicenter Clinical Trial

Por Demetri, George D., von Mehren, Margaret, Jones, Robin L., Hensley, Martee L., Schuetze, Scott M., Staddon, Arthur, Milhem, Mohammed, Elias, Anthony, Ganjoo, Kristen, Tawbi, Hussein, Van Tine, Brian A., Spira, Alexander, Dean, Andrew, Khokhar, Nushmia Z., Park, Youn Choi, Knoblauch, Roland E., Parekh, Trilok V., Maki, Robert G., Patel, Shreyaskumar R.
Publicado no J Clin Oncol (2016)