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1

Identification of active transcriptional regulatory elements with GRO-seq

Identification of active transcriptional regulatory elements with GRO-seq

Por Danko, Charles G., Hyland, Stephanie L., Core, Leighton J., Martins, Andre L., Waters, Colin T, Lee, Hyung Won, Cheung, Vivian G., Kraus, W. Lee, Lis, John T., Siepel, Adam
Publicado no Nat Methods (2015)

“...) with enrichment for 5'-capped RNAs reveals active TREs with high accuracy. Here, we demonstrate that active TREs...”
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2

Antibodies inside of a cell can change its outside: Can intrabodies provide a new therapeutic paradigm?

Antibodies inside of a cell can change its outside: Can intrabodies provide a new therapeutic paradigm?

Por Marschall, Andrea L.J., Dübel, Stefan
Publicado no Comput Struct Biotechnol J (2016)

“... new therapeutic strategies such as therapy with RNAi, CRISPR/Cas9 or antibody therapies as single...”
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3

An osteocalcin-deficient mouse strain without endocrine abnormalities

An osteocalcin-deficient mouse strain without endocrine abnormalities

Por Diegel, Cassandra R., Hann, Steven, Ayturk, Ugur M., Hu, Jennifer C. W., Lim, Kyung-eun, Droscha, Casey J., Madaj, Zachary B., Foxa, Gabrielle E., Izaguirre, Isaac, Transgenics Core, VAI Vivarium and, Paracha, Noorulain, Pidhaynyy, Bohdan, Dowd, Terry L., Robling, Alexander G., Warman, Matthew L., Williams, Bart O.
Publicado no PLoS Genet (2020)

“... by homologous recombination. Here we describe mice with a new Bglap and Bglap2 double-knockout (dko) allele...”
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4

Enhancing the Functionality of Core Labs with the SOLiD Sequencing System

Enhancing the Functionality of Core Labs with the SOLiD Sequencing System

Por Ziegle, J., Joe, L., Burcham, T., Alburo, A., Hendricks, C., Xu, L., Nutter, R.
Publicado em 2010

“... Resequencing applications can now be executed with these systems and are revolutionizing our understanding...”
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5

Electronic duality in strongly correlated matter

Electronic duality in strongly correlated matter

Por Park, T., Graf, M. J., Boulaevskii, L., Sarrao, J. L., Thompson, J. D.
Publicado em 2008

“... hand, magnetic order in a metal arises from electrons localized close to the ionic core and whose...”
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6

Systematic Extraction of Analogue Series from Large Compound Collections Using a New Computational Compound–Core Relationship Method

Systematic Extraction of Analogue Series from Large Compound Collections Using a New Computational Compound–Core Relationship Method

Por Naveja, J. Jesús, Vogt, Martin, Stumpfe, Dagmar, Medina-Franco, José L., Bajorath, Jürgen
Publicado no ACS Omega (2019)

“.... In addition to considering an analogue series (AS) or multiple series on a case-by-case basis, which is often...”
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7

New internal structure of spider dragline silk revealed by atomic force microscopy.

New internal structure of spider dragline silk revealed by atomic force microscopy.

Por Li, S F, McGhie, A J, Tang, S L
Publicado em 1994

“... of the dragline silk of Nephila clavipes from microtomed sections of the silk. Contrary to a previously proposed...”
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8

A general approach for retrosynthetic molecular core analysis

A general approach for retrosynthetic molecular core analysis

Por Naveja, J. Jesús, Pilón-Jiménez, B. Angélica, Bajorath, Jürgen, Medina-Franco, José L.
Publicado no J Cheminform (2019)

“... of retrosynthesis rules. Thereafter, a bipartite network consisting of molecules and cores can be constructed for a...”
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9

Dendritic Peptide Bolaamphiphiles for siRNA Delivery to Primary Adipocytes

Dendritic Peptide Bolaamphiphiles for siRNA Delivery to Primary Adipocytes

Por Eldredge, Alexander C., Johnson, Mark E., Cao, Yang, Zhang, Ling, Zhao, Can, Liu, Zhengxia, Yang, Qin, Guan, Zhibin
Publicado no Biomaterials (2018)

“... consists of two L-Lysine dendrons connected to a fluorocarbon core through disulfide linkages. The Lysine...”
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10

Effects of Valproic Acid Derivatives on Inositol Trisphosphate Depletion, Teratogenicity, Glycogen Synthase Kinase-3β Inhibition, and Viral Replication: A Screening Approach for New Bipolar Disorder Drugs Derived from the Valproic Acid Core Structure

Effects of Valproic Acid Derivatives on Inositol Trisphosphate Depletion, Teratogenicity, Glycogen Synthase Kinase-3β Inhibition, and Viral Replication: A Screening Approach for New Bipolar Disorder Drugs...

Por Eickholt, B. J., Towers, G. J., Ryves, W. J., Eikel, D., Adley, K., Ylinen, L. M. J., Chadborn, N. H., Harwood, A. J., Nau, H., Williams, R. S. B.
Publicado em 2005

“...Inositol-1,4,5-trisphosphate (InsP(3)) depletion has been implicated in the therapeutic action...”
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11

An internal ribosomal entry mechanism promotes translation of murine leukemia virus gag polyprotein precursors.

An internal ribosomal entry mechanism promotes translation of murine leukemia virus gag polyprotein precursors.

Por Berlioz, C, Darlix, J L
Publicado em 1995

“... to construct a new dicistronic retroviral vector in which the F-MLV leader can promote both packaging...”
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12

Engineering of software the continuing contributions of Leon J. Osterweil /

Engineering of software the continuing contributions of Leon J. Osterweil /

Por Tarr, Peri L., Wolf, Alexander L.
Publicado em 2011

“...Software engineering research can trace its roots to a few highly influential individuals. Among...”
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Livro

13

Sexual networks and sexually transmitted infections: A tale of two cities

Sexual networks and sexually transmitted infections: A tale of two cities

Por Jolly, A. M., Muth, S. Q., Wylie, J. L., Potterat, J. J.
Publicado em 2001

“..., peripheral to the core, may form the mechanism by which chlamydia can remain endemic, in contrast with larger...”
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14

Core–shell patterning of synthetic hydrogels via interfacial bioorthogonal chemistry for spatial control of stem cell behavior

Core–shell patterning of synthetic hydrogels via interfacial bioorthogonal chemistry for spatial control of stem cell behavior

Por Dicker, K. T., Song, J., Moore, A. C., Zhang, H., Li, Y., Burris, D. L., Jia, X., Fox, J. M.
Publicado no Chem Sci (2018)

“...A new technique is described for the patterning of cell-guidance cues in synthetic extracellular...”
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15

WAIS Divide ice core suggests sustained changes in the atmospheric formation pathways of sulfate and nitrate since the 19th century in the extratropical Southern Hemisphere

WAIS Divide ice core suggests sustained changes in the atmospheric formation pathways of sulfate...

Por E. D. Sofen, B. Alexander, E. J. Steig, M. H. Thiemens, S. A. Kunasek, H. M. Amos, A. J. Schauer, M. G. Hastings, J. Bautista, T. L. Jackson, L. E. Vogel, J. R. McConnell, D. R. Pasteris, E. S. Saltzman
Publicado em 2014-06-01

“... in the atmosphere. A new record of sulfate and nitrate Δ<sup>17</sup>O spanning the last 2400 years from the West...”
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16

The Origins of Cooperative Bacterial Communities

The Origins of Cooperative Bacterial Communities

Por Sachs, J. L., Hollowell, A. C.
Publicado em 2012

“..., called the Black Queen Hypothesis, gives a new perspective on this debate (J. J. Morris, R. E. Lenski...”
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17

Structure and conformational plasticity of the U6 small nuclear ribonucleoprotein core

Structure and conformational plasticity of the U6 small nuclear ribonucleoprotein core

Por Montemayor, Eric J., Didychuk, Allison L., Liao, Honghong, Hu, Panzhou, Brow, David A., Butcher, Samuel E.
Publicado no Acta Crystallogr D Struct Biol (2017)

“...) so that it can pair with U4 snRNA. A previously reported crystal structure of the ‘core’ of the U6...”
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18

Hepatitis B virus transcript produced by RNA splicing.

Hepatitis B virus transcript produced by RNA splicing.

Por Su, T S, Lai, C J, Huang, J L, Lin, L H, Yauk, Y K, Chang, C M, Lo, S J, Han, S H
Publicado em 1989

“... of the cDNA of the 2.2-kilobase RNA suggests that this transcript can potentially encode a new protein...”
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19

A quantitative real-time PCR assay for the identification and enumeration of Alexandrium cysts in marine sediments

A quantitative real-time PCR assay for the identification and enumeration of Alexandrium cysts in marine sediments

Por Erdner, D.L., Percy, L., Keafer, B., Lewis, J., Anderson, D.M.
Publicado em 2010

“... from the sediment. The resulting assay shows a linear response over 6 orders of magnitude and can...”
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20

Investigating the Potential Influence of Cause of Death and Cocaine Levels on the Differential Expression of Genes Associated with Cocaine Abuse

Investigating the Potential Influence of Cause of Death and Cocaine Levels on the Differential Expression of Genes Associated with Cocaine Abuse

Por Bannon, Michael J., Savonen, Candace L., Hartley, Zachary J., Johnson, Magen M., Schmidt, Carl J.
Publicado no PLoS One (2015)

“... pathophysiology. Although the study of postmortem human brain represents a unique resource in this regard, it can...”
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