Effects of Valproic Acid Derivatives on Inositol Trisphosphate Depletion, Teratogenicity, Glycogen Synthase Kinase-3β Inhibition, and Viral Replication: A Screening Approach for New Bipolar Disorder Drugs Derived from the Valproic Acid Core Structure

Inositol-1,4,5-trisphosphate (InsP(3)) depletion has been implicated in the therapeutic action of bipolar disorder drugs, including valproic acid (VPA). It is not currently known whether the effect of VPA on InsP(3) depletion is related to the deleterious effects of teratogenicity or elevated viral...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Eickholt, B. J., Towers, G. J., Ryves, W. J., Eikel, D., Adley, K., Ylinen, L. M. J., Chadborn, N. H., Harwood, A. J., Nau, H., Williams, R. S. B.
Format: Artigo
Sprog:Inglês
Udgivet: 2005
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1360212/
https://ncbi.nlm.nih.gov/pubmed/15687223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.104.009308
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker