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GSK-3 activity in neocortical cells is inhibited by lithium but not carbamazepine or valproic acid
OBJECTIVES: Lithium (Li(+)) has been suggested to target the enzyme glycogen synthase kinase 3 (GSK-3) as a mechanism of mood stabilization. Inhibition of GSK-3 by a second mood-stabilizer, valproic acid (VPA), has also been reported, but this effect is dependent on cell type. It is currently unknow...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2005
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1249491/ https://ncbi.nlm.nih.gov/pubmed/15898963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1399-5618.2005.00194.x |
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