The Embryonic Stem Cell Test as Tool to Assess Structure-Dependent Teratogenicity: The Case of Valproic Acid

Teratogenicity can be predicted in vitro using the embryonic stem cell test (EST). The EST, which is based on the morphometric measurement of cardiomyocyte differentiation and cytotoxicity parameters, represents a scientifically validated method for the detection and classification of chemicals acco...

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Detalhes bibliográficos
Main Authors: Riebeling, Christian, Pirow, Ralph, Becker, Klaus, Buesen, Roland, Eikel, Daniel, Kaltenhäuser, Johanna, Meyer, Frauke, Nau, Heinz, Slawik, Birgitta, Visan, Anke, Volland, Jutta, Spielmann, Horst, Luch, Andreas, Seiler, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
IN VITRO Methods and Alternatives to Animals
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061479/
https://ncbi.nlm.nih.gov/pubmed/21227905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfr001
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