The Embryonic Stem Cell Test as Tool to Assess Structure-Dependent Teratogenicity: The Case of Valproic Acid

Teratogenicity can be predicted in vitro using the embryonic stem cell test (EST). The EST, which is based on the morphometric measurement of cardiomyocyte differentiation and cytotoxicity parameters, represents a scientifically validated method for the detection and classification of chemicals acco...

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Autors principals: Riebeling, Christian, Pirow, Ralph, Becker, Klaus, Buesen, Roland, Eikel, Daniel, Kaltenhäuser, Johanna, Meyer, Frauke, Nau, Heinz, Slawik, Birgitta, Visan, Anke, Volland, Jutta, Spielmann, Horst, Luch, Andreas, Seiler, Andrea
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2011
Matèries:
IN VITRO Methods and Alternatives to Animals
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061479/
https://ncbi.nlm.nih.gov/pubmed/21227905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfr001
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