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Antibodies inside of a cell can change its outside: Can intrabodies provide a new therapeutic paradigm?

Challenges posed by complex diseases such as cancer, chronic viral infections, neurodegenerative disorders and many others have forced researchers to think beyond classic small molecule drugs, exploring new therapeutic strategies such as therapy with RNAi, CRISPR/Cas9 or antibody therapies as single...

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Detalhes bibliográficos
Publicado no:Comput Struct Biotechnol J
Main Authors: Marschall, Andrea L.J., Dübel, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: Research Network of Computational and Structural Biotechnology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990636/
https://ncbi.nlm.nih.gov/pubmed/27570612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2016.07.003
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