Functional knock down of VCAM1 in mice mediated by endoplasmatic reticulum retained intrabodies

Functional knockdowns mediated by endoplasmatic reticulum-retained antibodies (ER intrabodies) are a promising tool for research because they allow functional interference on the protein level. We demonstrate for the first time that ER intrabodies can induce a knock-down phenotype in mice. Surface V...

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Detalhes bibliográficos
Publicado no:MAbs
Main Authors: Marschall, Andrea LJ, Single, Frank N, Schlarmann, Katrin, Bosio, Andreas, Strebe, Nina, van den Heuvel, Joop, Frenzel, André, Dübel, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
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Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622715/
https://ncbi.nlm.nih.gov/pubmed/25484057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.34377
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