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1

CSI: Cancer Signature Investigation: ERBB2 (HER2)-Activating Mutation and Amplification-Positive Breast Carcinoma Mimicking Lung Primary

CSI: Cancer Signature Investigation: ERBB2 (HER2)-Activating Mutation and Amplification-Positive Breast Carcinoma Mimicking Lung Primary

Por Shih, Jennifer, Bashir, Babar, Gustafson, Karen S., Andrake, Mark, Dunbrack, Roland L., Goldstein, Lori J., Boumber, Yanis
Publicado no J Natl Compr Canc Netw (2015)

“... of the workup, the tumor was analyzed by a 50-gene targeted mutation panel, which detected 3 somatic mutations...”
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2

A Distributed Network for Intensive Longitudinal Monitoring in Metastatic Triple-Negative Breast Cancer

A Distributed Network for Intensive Longitudinal Monitoring in Metastatic Triple-Negative Breast Cancer

Por Blau, C. Anthony, Ramirez, Arturo B., Blau, Sibel, Pritchard, Colin C., Dorschner, Michael O., Schmechel, Stephen C., Martins, Timothy J., Mahen, Elisabeth M., Burton, Kimberly A., Komashko, Vitalina M., Radenbaugh, Amie J., Dougherty, Katy, Thomas, Anju, Miller, Christopher P., Annis, James, Fromm, Jonathan R., Song, Chaozhong, Chang, Elizabeth, Howard, Kellie, Austin, Sharon, Schmidt, Rodney A., Linenberger, Michael L., Becker, Pamela S., Senecal, Francis M., Mecham, Brigham H., Lee, Su-In, Madan, Anup, Ronen, Roy, Dutkowski, Janusz, Heimfeld, Shelly, Wood, Brent L., Stilwell, Jackie L., Kaldjian, Eric P., Haussler, David, Zhu, Jingchun
Publicado no J Natl Compr Canc Netw (2016)

“... patient with cancer can generate high-resolution views of the natural history of cancer and suggest new...”
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3

In Silico Identification and Characterization of a Hypothetical Protein From Revealing S-Adenosylmethionine-Dependent Methyltransferase Activity

In Silico Identification and Characterization of a Hypothetical Protein From Revealing S-Adenosylmethionine-Dependent Methyltransferase Activity

Por Spencer Mark Mondol, Depro Das, Durdana Mahin Priom, M Shaminur Rahman, M Rafiul Islam, Md Mizanur Rahaman
Publicado em 2022-04-01

“... unveiled its association with NADH-ubiquinone oxidoreductase (Complex I). The assembly and regulation...”
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4

Caracterização química de novos genótipos de maracujá e produção de um suco com baixa adição de açúcar /

Caracterização química de novos genótipos de maracujá e produção de um suco com baixa adição de açúcar /

Por Mamede, Alexandra Mara Goulart Nunes., Farah, Adriana, Soares, Antonio Gomes, Universidade Federal do Rio de Janeiro.
Publicado em 2012

“.... In Chapter 2, the volatile composition of new genotypes of yellow (BRS GA, BGM J18), purple (BGM022, BGM023...”
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5

Manipulating Metallogel Properties by Luminogens and Their Applications in Cell Imaging

Manipulating Metallogel Properties by Luminogens and Their Applications in Cell Imaging

Por Biswas, Arnab, Mukhopadhyay, Sujay, Singh, Roop Shikha, Kumar, Ashish, Rana, Nishant Kumar, Koch, Biplob, Pandey, Daya Shankar
Publicado no ACS Omega (2018)

“.... Cytotoxicity measurements and imaging against breast cancer cell line MDA-MB-231 unveiled that three out...”
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6

The 1.4-Å crystal structure of the S. pombe Pop2p deadenylase subunit unveils the configuration of an active enzyme

The 1.4-Å crystal structure of the S. pombe Pop2p deadenylase subunit unveils the configuration of an active enzyme

Por Jonstrup, Anette Thyssen, Andersen, Kasper R., Van, Lan B., Brodersen, Ditlev E.
Publicado em 2007

“... by the mega-Dalton Ccr4-Not complex, of which both the Ccr4p and Pop2p subunits are 3′–5′ exonucleases...”
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7

Chemotherapy overcomes TRAIL-R4-mediated TRAIL resistance at the DISC level

Chemotherapy overcomes TRAIL-R4-mediated TRAIL resistance at the DISC level

Por Morizot, A, Mérino, D, Lalaoui, N, Jacquemin, G, Granci, V, Iessi, E, Lanneau, D, Bouyer, F, Solary, E, Chauffert, B, Saas, P, Garrido, C, Micheau, O
Publicado em 2011

“... that are often expressed by tumor cells. TRAIL can also bind non-functional receptors such as TRAIL-R4...”
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8

Protein lipoxidation: Detection strategies and challenges

Protein lipoxidation: Detection strategies and challenges

Por Aldini, Giancarlo, Domingues, M. Rosário, Spickett, Corinne M., Domingues, Pedro, Altomare, Alessandra, Sánchez-Gómez, Francisco J., Oeste, Clara L., Pérez-Sala, Dolores
Publicado no Redox Biol (2015)

“...Enzymatic and non-enzymatic lipid metabolism can give rise to reactive species that may covalently...”
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9

Structural basis of the chromodomain of Cbx3 bound to methylated peptides from histone h1 and G9a.

Structural basis of the chromodomain of Cbx3 bound to methylated peptides from histone h1 and G9a.

Por Jianbin Ruan, Hui Ouyang, Maria F Amaya, Mani Ravichandran, Peter Loppnau, Jinrong Min, Jianye Zang
Publicado em 2012-01-01

“... that the Cbx3 chromodomain can bind to H1K26me2 and G9aK185me3 with comparable binding affinities compared to H...”
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10

Systems-level interactions between insulin–EGF networks amplify mitogenic signaling

Systems-level interactions between insulin–EGF networks amplify mitogenic signaling

Por Borisov, Nikolay, Aksamitiene, Edita, Kiyatkin, Anatoly, Legewie, Stefan, Berkhout, Jan, Maiwald, Thomas, Kaimachnikov, Nikolai P, Timmer, Jens, Hoek, Jan B, Kholodenko, Boris N
Publicado em 2009

“..., and phosphatase SHP2, convert insulin-induced increase in the phosphatidylinositol-3,4,5-triphosphate (PIP(3...”
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11

Decoding the genome with an integrative analysis tool: Combinatorial CRM Decoder

Decoding the genome with an integrative analysis tool: Combinatorial CRM Decoder

Por Kang, Keunsoo, Kim, Joomyeong, Chung, Jae Hoon, Lee, Daeyoup
Publicado em 2011

“.... Although integrative analysis of available genome-wide information can provide new biological insights...”
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12

Preclinical and Clinical Epigenetic-Based Reconsideration of Beckwith-Wiedemann Syndrome

Preclinical and Clinical Epigenetic-Based Reconsideration of Beckwith-Wiedemann Syndrome

Por Chiara Papulino, Ugo Chianese, Maria Maddalena Nicoletti, Rosaria Benedetti, Lucia Altucci
Publicado em 2020-09-01

“... unveil new therapeutic options for BWS patients. Although the complexity of the syndrome is high...”
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13

Genome-wide association mapping of salinity tolerance in rice (Oryza sativa)

Genome-wide association mapping of salinity tolerance in rice (Oryza sativa)

Por Kumar, Vinod, Singh, Anshuman, Mithra, S. V. Amitha, Krishnamurthy, S. L., Parida, Swarup K., Jain, Sourabh, Tiwari, Kapil K., Kumar, Pankaj, Rao, Atmakuri R., Sharma, S. K., Khurana, Jitendra P., Singh, Nagendra K., Mohapatra, Trilochan
Publicado no DNA Res (2015)

“... to various reasons. It is a complex quantitative trait having different components, which can be dissected...”
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14

$Plasminogen activator urokinase expression reveals TRAIL responsiveness and supports fractional survival of cancer cells$

Plasminogen activator urokinase expression reveals TRAIL responsiveness and supports fractional survival of cancer cells

Por Pavet, V, Shlyakhtina, Y, He, T, Ceschin, D G, Kohonen, P, Perälä, M, Kallioniemi, O, Gronemeyer, H
Publicado em 2014

“...Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL/TNFSF10/Apo2L) holds promise...”
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15

A Systems Biology Approach to Deciphering the Etiology of Steatosis Employing Patient-Derived Dermal Fibroblasts and iPS Cells

A Systems Biology Approach to Deciphering the Etiology of Steatosis Employing Patient-Derived Dermal Fibroblasts and iPS Cells

Por Jozefczuk, Justyna, Kashofer, Karl, Ummanni, Ramesh, Henjes, Frauke, Rehman, Samrina, Geenen, Suzanne, Wruck, Wasco, Regenbrecht, Christian, Daskalaki, Andriani, Wierling, Christoph, Turano, Paola, Bertini, Ivano, Korf, Ulrike, Zatloukal, Kurt, Westerhoff, Hans V., Lehrach, Hans, Adjaye, James
Publicado em 2012

“... reconstruction, and data management can be employed to unveil the mechanisms underlying the progression...”
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16

Fixed Volume or Fixed Pressure: A Murine Model of Hemorrhagic Shock

Fixed Volume or Fixed Pressure: A Murine Model of Hemorrhagic Shock

Por Kohut, Lauryn K., Darwiche, Sophie S., Brumfield, John M., Frank, Alicia M., Billiar, Timothy R.
Publicado em 2011

“... of detrimental signaling events often resulting in mortality. (1, 2, 3, 4, 5) These signaling events can also...”
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17

Maintenance of Genome Integrity: DNA Damage Sensing, Signaling, Repair and Replication in Plants

Maintenance of Genome Integrity: DNA Damage Sensing, Signaling, Repair and Replication in Plants

Por Anca Macovei, Alma Balestrazzi, Ayako N. Sakamoto, V. Mohan Murali Achary, Kaoru Okamoto Yoshiyama
Publicado no Frontiers Research Topics (2016)

“...Environmental stresses and metabolic by-products can severely affect the integrity of genetic...”
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