Preclinical and Clinical Epigenetic-Based Reconsideration of Beckwith-Wiedemann Syndrome

Epigenetics has achieved a profound impact in the biomedical field, providing new experimental opportunities and innovative therapeutic strategies to face a plethora of diseases. In the rare diseases scenario, Beckwith-Wiedemann syndrome (BWS) is a pediatric pathological condition characterized by a...

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Detalhes bibliográficos
Main Authors: Chiara Papulino, Ugo Chianese, Maria Maddalena Nicoletti, Rosaria Benedetti, Lucia Altucci
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020-09-01
Colecção:Frontiers in Genetics
Assuntos:
Beckwith-Wiedemann syndrome
rare diseases
cancer predisposition
epigenetics
metabolic disorders
DNA methylation
Acesso em linha:https://www.frontiersin.org/article/10.3389/fgene.2020.563718/full
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