Resultados da pesquisa - (( j a camp can now ) OR ((( j nayl clamp j now ) OR ( j led con ((canada ne) OR (canada nee)) ))))

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Ecto-5′-Nucleotidase (CD73)-Mediated Formation of Adenosine Is Critical for the Striatal Adenosine A(2A) Receptor Functions

Por Augusto, Elisabete, Matos, Marco, Sévigny, Jean, El-Tayeb, Ali, Bynoe, Margaret S., Müller, Christa E., Cunha, Rodrigo A., Chen, Jiang-Fan
Publicado em 2013

“... activating A(2A)Rs is unknown. We now show that ecto-5′-nucleotidase (CD73), the major enzyme able to convert...”
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Nitric oxide and atrial natriuretic factor stimulate cGMP-dependent membrane insertion of aquaporin 2 in renal epithelial cells

Por Bouley, Richard, Breton, Sylvie, Sun, Tian-xiao, McLaughlin, Margaret, Nsumu, Ndona N., Lin, Herbert Y., Ausiello, Dennis A., Brown, Dennis
Publicado em 2000

“... cAMP, activating protein kinase A (PKA) to phosphorylate AQP2 on the COOH-terminal residue, serine 256...”
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The metabolic/pH sensor soluble adenylyl cyclase is a tumor suppressor protein

Por Ramos-Espiritu, Lavoisier, Diaz, Ana, Nardin, Charlee, Saviola, Anthony J., Shaw, Fiona, Plitt, Tamar, Yang, Xia, Wolchok, Jedd, Pirog, Edyta C., Desman, Garrett, Sboner, Andrea, Zhang, Tuo, Xiang, Jenny, Merghoub, Taha, Levin, Lonny R., Buck, Jochen, Zippin, Jonathan H.
Publicado no Oncotarget (2016)

“...cAMP signaling pathways can both stimulate and inhibit the development of cancer; however...”
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Extracellular vesicles direct migration by synthesizing and releasing chemotactic signals

Por Kriebel, Paul W., Majumdar, Ritankar, Jenkins, Lisa M., Senoo, Hiroshi, Wang, Weiye, Ammu, Sonia, Chen, Song, Narayan, Kedar, Iijima, Miho, Parent, Carole A.
Publicado no J Cell Biol (2018)

“... demonstrate that the released vesicles not only contain cAMP but also can actively synthesize and release cAMP...”
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Poster Session A

Publicado no Mol Cell Proteomics (2017)

“... and sample loss. Due to the straightforward nature, the method can readily be performed in a 96-well format...”
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Guanfacine for the Treatment of Cognitive Disorders: A Century of Discoveries at Yale

Por Arnsten, Amy F.T., Jin, Lu E.
Publicado em 2012

“... has found that the noradrenergic α2A agonist guanfacine can improve PFC function by strengthening PFC...”
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Chemical factors that influence nucleocytoplasmic transport: a fluorescence photobleaching study

Publicado em 1986

“... that concanavalin A, but not wheat germ or soybean agglutinin, can block dextran transport completely. The effectors...”
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Predictability of spatio-temporal patterns in a lattice of coupled FitzHugh–Nagumo oscillators

Por Grace, Miriam, Hütt, Marc-Thorsten
Publicado em 2013

“... spatio-temporal patterns (in their example, spiral waves of cAMP in a colony of Dictyostelium discoideum...”
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GBPI, a novel gastrointestinal- and brain-specific PP1-inhibitory protein, is activated by PKC and inactivated by PKA.

Por Liu, Qing-Rong, Zhang, Ping-Wu, Lin, Zhicheng, Li, Qi-Fu, Woods, Amina S, Troncoso, Juan, Uhl, George R
Publicado em 2004

“... regulated by phosphorylation. We now describe a novel PKC (protein kinase C)-dependent PP1 inhibitor, namely...”
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Distribution of ABO and Rh types in voluntary Blood donors in Jharkhand area as a study conducted by RIMS, Ranchi

Por Singh, Anu, Srivastava, Ramesh Kumar, Deogharia, Kabita S., Singh, Kranti Kumar
Publicado no J Family Med Prim Care (2016)

“... be maintained so that no patient dies due to lack of a particular blood group. CONTEXT: Up till now about 400...”
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14-3-3ε Couples Protein Kinase A to Semaphorin Signaling and Silences Plexin RasGAP-mediated Axonal Repulsion

Por Yang, Taehong, Terman, Jonathan R.
Publicado em 2012

“... these events. We now uncover a simple biochemical switch that controls Semaphorin/Plexin repulsive guidance...”
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The T alpha 2 nuclear protein binding site from the human T cell receptor alpha enhancer functions as both a T cell-specific transcriptional activator and repressor

Publicado em 1990

“... activity of the enhancer. The T alpha 1 binding site contains a consensus cAMP response element (CRE...”
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The role of cyclic AMP signaling in promoting axonal regeneration after spinal cord injury

Por Hannila, Sari S., Filbin, Marie T.
Publicado em 2007

“... in the CNS. Intracellular cAMP levels can be increased through a peripheral conditioning lesion...”
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Treating COPD with PDE 4 inhibitors

Por Brown, William M
Publicado em 2007

“..., and pulmonary vasculature. Elevated levels of the second messenger cAMP can inhibit some inflammatory processes...”
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Regulation of nephron water and electrolyte transport by adenylyl cyclases

Por Rieg, Timo, Kohan, Donald E.
Publicado em 2014

“...Adenylyl cyclases (AC) catalyze formation of cAMP, a critical component of G protein-coupled...”
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Emergency Health Services Informational and Educational Programs: Development and Present Status

Por Pace, F. C.
Publicado em 1967

“... programs are discussed. Instituted in 1951 for medical and dental practitioners at a military school...”
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Analysis of functional neuronal connectivity in the Drosophila brain

Por Yao, Zepeng, Macara, Ann Marie, Lelito, Katherine R., Minosyan, Tamara Y., Shafer, Orie T.
Publicado em 2012

“... larval and adult brains. This technically facile approach can now be used in wild-type and mutant genetic...”
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Desensitization of the insulin receptor by antireceptor antibodies in vivo is blocked by treatment of mice with beta-adrenergic agonists.

Por Elias, D, Rapoport, M, Cohen, I R, Shechter, Y
Publicado em 1988

“..., and Y. Shechter. 1984, J. Biol. Chem. 259: 6411-6419). We now report that effects of the antiidiotypic...”
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Structural Basis for the Design of Selective Phosphodiesterase 4B Inhibitors

Por Fox, David, Burgin, Alex B., Gurney, Mark E.
Publicado em 2013

“... PDE4 subtypes (PDE4A-D). We show that highly selective PDE4B inhibitors can be designed by exploiting...”
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AKAP79 Interacts with Multiple Adenylyl Cyclase (AC) Isoforms and Scaffolds AC5 and -6 to α-Amino-3-hydroxyl-5-methyl-4-isoxazole-propionate (AMPA) Receptors

Por Efendiev, Riad, Samelson, Bret K., Nguyen, Bao T., Phatarpekar, Prasad V., Baameur, Faiza, Scott, John D., Dessauer, Carmen W.
Publicado em 2010

“...Spatiotemporal specificity of cAMP action is best explained by targeting protein kinase A (PKA...”
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