Ecto-5′-Nucleotidase (CD73)-Mediated Formation of Adenosine Is Critical for the Striatal Adenosine A(2A) Receptor Functions

Adenosine is a neuromodulator acting through inhibitory A(1) receptors (A(1)Rs) and facilitatory A(2A)Rs, which have similar affinities for adenosine. It has been shown that the activity of intracellular adenosine kinase preferentially controls the activation of A(1)Rs, but the source of the adenosi...

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Main Authors: Augusto, Elisabete, Matos, Marco, Sévigny, Jean, El-Tayeb, Ali, Bynoe, Margaret S., Müller, Christa E., Cunha, Rodrigo A., Chen, Jiang-Fan
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724543/
https://ncbi.nlm.nih.gov/pubmed/23843511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5817-12.2013
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