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Reduced striatal ecto-nucleotidase activity in schizophrenia patients supports the “adenosine hypothesis”
Schizophrenia (SZ) is a major chronic neuropsychiatric disorder characterized by a hyperdopaminergic state. The hypoadenosinergic hypothesis proposes that reduced extracellular adenosine levels contribute to dopamine D(2) receptor hyperactivity. ATP, through the action of ecto-nucleotidases, constit...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Netherlands
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3889387/ https://ncbi.nlm.nih.gov/pubmed/23771238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-013-9370-7 |
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