Resultados da pesquisa - (( ian m vez a ) OR ( jan a lei

1

Somatic Mutagenesis in Mammals and Its Implications for Human Disease and Aging

Por Zhang, Lei, Vijg, Jan
Publicado no Annu Rev Genet (2018)

“...DNA mutations as a consequence of errors during DNA damage repair, replication, or mitosis...”
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A high-fidelity method for genomic sequencing of single somatic cells reveals a very high mutational burden

Por Vijg, Jan, Dong, Xiao, Zhang, Lei
Publicado no Exp Biol Med (Maywood) (2017)

“.... Here, we review the available assays for measuring somatic mutations, with a focus on recent single...”
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On the hydrogen activation by frustrated Lewis pairs in the solid state: benchmark studies and theoretical insights

Por Liu, Lei, Brandenburg, Jan Gerit, Grimme, Stefan
Publicado no Philos Trans A Math Phys Eng Sci (2017)

“... expanded to the solid state showing a variety of interesting reactivities. Therefore, there is a need...”
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Genome instability: a conserved mechanism of ageing?

Por Vijg, Jan, Dong, Xiao, Milholland, Brandon, Zhang, Lei
Publicado no Essays Biochem (2017)

“... for evolution through natural selection but are also a source of deleterious effects. It has since long been...”
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Biofilm Bridges Forming Structural Networks on Patterned Lubricant‐Infused Surfaces

Por Lei, Wenxi, Bruchmann, Julia, Rüping, Jan Lars, Levkin, Pavel A., Schwartz, Thomas
Publicado no Adv Sci (Weinh) (2019)

“... lubricant‐infused regions by using a mechanism, termed “biofilm bridges”. Here, it is demonstrated...”
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Health hazards of China’s lead-acid battery industry: a review of its market drivers, production processes, and health impacts

Por van der Kuijp, Tsering Jan, Huang, Lei, Cherry, Christopher R
Publicado em 2013

“... of China’s rising lead-acid battery industry on lead pollution and exposure. It starts with a synthesis...”
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Functional Studies of a Fibrinogen Binding Protein from Staphylococcus epidermidis

Por Pei, Lei, Palma, Marco, Nilsson, Martin, Guss, Bengt, Flock, Jan-Ingmar
Publicado em 1999

“...A gene encoding a fibrinogen binding protein from Staphylococcus epidermidis was previously cloned...”
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Protonation Dynamics on Lipid Nanodiscs: Influence of the Membrane Surface Area and External Buffers

Por Xu, Lei, Öjemyr, Linda Näsvik, Bergstrand, Jan, Brzezinski, Peter, Widengren, Jerker
Publicado no Biophys J (2016)

“... on a local scale, analyzing fluorescence fluctuations of individual pH-sensitive fluorophores...”
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A Fibrinogen-Binding Protein of Staphylococcus epidermidis

Por Nilsson, Martin, Frykberg, Lars, Flock, Jan-Ingmar, Pei, Lei, Lindberg, Martin, Guss, Bengt
Publicado em 1998

“... activity, a shotgun phage display library covering the S. epidermidis chromosome was constructed...”
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Differences between germline and somatic mutation rates in humans and mice

Por Milholland, Brandon, Dong, Xiao, Zhang, Lei, Hao, Xiaoxiao, Suh, Yousin, Vijg, Jan
Publicado no Nat Commun (2017)

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Single-cell whole-genome sequencing reveals the functional landscape of somatic mutations in B lymphocytes across the human lifespan

Por Zhang, Lei, Dong, Xiao, Lee, Moonsook, Maslov, Alexander Y., Wang, Tao, Vijg, Jan
Publicado no Proc Natl Acad Sci U S A (2019)

“...Accumulation of mutations in somatic cells has been implicated as a cause of aging since the 1950...”
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Reversible Disruption of Specific Transcription Factor-DNA Interactions Using CRISPR/Cas9

Por Shariati, S. Ali, Dominguez, Antonia, Xie, Shicong, Wernig, Marius, Qi, Lei S., Skotheim, Jan M.
Publicado no Mol Cell (2019)

“... to specific sites, a method we term CRISPRd. Since CRISPR guide RNAs are longer than transcription factor...”
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The Anti-Tumor Activity of a Neutralizing Nanobody Targeting Leptin Receptor in a Mouse Model of Melanoma

Por McMurphy, Travis, Xiao, Run, Magee, Daniel, Slater, Andrew, Zabeau, Lennart, Tavernier, Jan, Cao, Lei
Publicado em 2014

“...Environmental and genetic activation of a brain-adipocyte axis inhibits cancer progression. Leptin...”
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Structure-based redesign of docking domain interactions modulates the product spectrum of a rhabdopeptide-synthesizing NRPS

Por Hacker, Carolin, Cai, Xiaofeng, Kegler, Carsten, Zhao, Lei, Weickhmann, A. Katharina, Wurm, Jan Philip, Bode, Helge B., Wöhnert, Jens
Publicado no Nat Commun (2018)

“...). In these systems multiple NRPS subunits interact with each other in a specific linear order mediated by specific...”
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Construction and selection of subtracted cDNA library of mouse hepatocarcinoma cell lines with different lymphatic metastasis potential

Por Hou, Li, Tang, Jan-Wu, Cui, Xiao-Nan, Wang, Bo, Song, Bo, Sun, Lei
Publicado no World J Gastroenterol (2004)

“... with different lymphatic metastasis potential. METHODS: cDNA of Hca-F cells was used as a tester and cDNA of Hca...”
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Systematic medical assessment, referral and treatment for diabetes care in China using lay family health promoters: protocol for the SMARTDiabetes cluster randomised controlled tri...

Por Peiris, David, Sun, Lei, Patel, Anushka, Tian, Maoyi, Essue, Beverley, Jan, Stephen, Zhang, Puhong
Publicado no Implement Sci (2016)

“... will be implemented as a cluster randomised controlled trial involving 80 communities (40 communities in Beijing...”
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Electrical Guidance of Human Stem Cells in the Rat Brain

Por Feng, Jun-Feng, Liu, Jing, Zhang, Lei, Jiang, Ji-Yao, Russell, Michael, Lyeth, Bruce G., Nolta, Jan A., Zhao, Min
Publicado no Stem Cell Reports (2017)

“...Limited migration of neural stem cells in adult brain is a roadblock for the use of stem cell...”
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Using a ‘no drain’ policy in 342 laparoscopic hepatectomies: which factors predict failure?

Por Ishizawa, Takeaki, Zuker, Noah B, Conrad, Claudius, Lei, Hao-Jan, Ciacio, Oriana, Kokudo, Norihiro, Gayet, Brice
Publicado em 2014

“...OBJECTIVES: The aim of this study was to identify factors that predict the failure of a ‘no drain...”
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The anticoagulant activation of antithrombin by heparin

Por Jin, Lei, Abrahams, Jan Pieter, Skinner, Richard, Petitou, Maurice, Pike, Robert N., Carrell, Robin W.
Publicado em 1997

“...Antithrombin, a plasma serpin, is relatively inactive as an inhibitor of the coagulation proteases...”
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Using Spin-Coated Silver Nanoparticles/Zinc Oxide Thin Films to Improve the Efficiency of GaInP/(In)GaAs/Ge Solar Cells

Por Lei, Po-Hsun, Chen, I-Jen, Chen, Jia-Jan, Yang, Po-Chun, Gong, Yan-Hua
Publicado no Materials (Basel) (2018)

“... films prepared using a treatment solution of 0.0008 M AgNO(3), 0.007 M Zn(CH(3)COO)(2), and 1 M NaOH...”
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