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1
“... required to conduct large and expensive clinical trials to “defend” the safety of their new drug when...”
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2
“... of the human genome, the complexities of disease at the individual level have made it difficult to utilize...”
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3
Por Carreón, Yojana J. P., Ríos-Ramírez, Maricarmen, Moctezuma, R. E., González-Gutiérrez, Jorge
Publicado no Sci Rep (2018)
“... and new strategies for diagnostic in patients. For such purpose, the development and implementation...”Publicado no Sci Rep (2018)
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4
“...The importance of trade and investment agreements for health is now widely acknowledged...”
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5
“... this applies to A(2A) adenosine receptors (ARs) and to P2Y(1) and P2Y(12) receptors (P2YRs) for ADP. These X...”
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6
Por Scheepers, H P A, Neerup Handlos, V, Schutjens, M H, Neef, C
Publicado no Eur J Hosp Pharm (2017)
“.... In order not to obstruct patient care, the Dutch Inspectorate has sent a Circular Letter on large-scale...”Publicado no Eur J Hosp Pharm (2017)
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7
“... by allowing the rate of cross-bridge-attachment to vary with velocity. The effects of [ATP], [ADP], and [P(i...”
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8
Por Coleman, Robert L, Oza, Amit M, Lorusso, Domenica, Aghajanian, Carol, Oaknin, Ana, Dean, Andrew, Colombo, Nicoletta, Weberpals, Johanne I, Clamp, Andrew, Scambia, Giovanni, Leary, Alexandra, Holloway, Robert W, Gancedo, Margarita Amenedo, Fong, Peter C, Goh, Jeffrey C, O’Malley, David M, Armstrong, Deborah K, Garcia-Donas, Jesus, Swisher, Elizabeth M, Floquet, Anne, Konecny, Gottfried E, McNeish, Iain A, Scott, Clare L, Cameron, Terri, Maloney, Lara, Isaacson, Jeff, Goble, Sandra, Grace, Caroline, Harding, Thomas C, Raponi, Mitch, Sun, James, Lin, Kevin K, Giordano, Heidi, Ledermann, Jonathan A
Publicado no Lancet (2017)
“... with a poly(ADP-ribose) polymerase inhibitor. We randomly allocated patients 2:1 to receive oral...”Publicado no Lancet (2017)
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9
Por Hammond, Robert G., Tan, Xuan, Chan, Matthew, Goel, Anupam, Johnson, Margaret A.
Publicado no Poly(ADP-Ribose) Polymerase (2017)
“... on poly(ADP-ribose), ADP-ribosylated proteins, and other metabolites of nicotinamide adenine dinucleotide...”Publicado no Poly(ADP-Ribose) Polymerase (2017)
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10
Por Martinez, Betsy, Tomkins, Jeffrey, Wackett, Lawrence P., Wing, Rod, Sadowsky, Michael J.
Publicado em 2001
“... acid. Computational analyses indicated that pADP-1 encodes 104 putative open reading frames (ORFs...”Publicado em 2001
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11
“...Collaborative target tracking is one of the most important applications of wireless sensor networks...”
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12
“...) that functions as a receptor for adenosine 5′-diphosphate (ADP). An antagonist of P2Y(1)R might potentially have...”
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13
Por Shihao Yao, Qiuzi Yi, Boyuan Ma, Xiaoting Mao, Ye Chen, Min-Xin Guan, Xiaohui Cang
Publicado em 2022-01-01
Assuntos:
“...Mitochondrial ADP...”Publicado em 2022-01-01
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14
Por Robert Rockenfeller, Michael Günther, Michael Günther, Norman Stutzig, Daniel F. B. Haeufle, Tobias Siebert, Syn Schmitt, Kay Leichsenring, Markus Böl, Thomas Götz
Publicado em 2020-05-01
“... (ATP). The reaction products, adenosine diphosphate (ADP) and inorganic phosphate (Pi), are then used...”Publicado em 2020-05-01
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15
“... the structure of full-length cholix toxin in complex with NAD(+) and proposed a new kinetic model for cholix...”
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16
“... understood. Here, we report a computational study of three representative groups of tyrosine in ADP...”
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17
“... computational screening to discover new PARP inhibitors. Among the 11,247 compounds analyzed, one natural...”
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18
Apparent Km of mitochondria for oxygen computed from Vmax measured in permeabilized muscle fibers...
Por Zoll, Joffrey, Bouitbir, Jamal, Sirvent, Pascal, Klein, Alexis, Charton, Antoine, Jimenez, Liliana, Péronnet, François R, Geny, Bernard, Richard, Ruddy
Publicado no Drug Des Devel Ther (2015)
“... in O(2) by a new electrolytic process because of O(2) trapping in water superstructures (clathrates...”Publicado no Drug Des Devel Ther (2015)
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19
Por Wei, An-Chi, Aon, Miguel A., O'Rourke, Brian, Winslow, Raimond L., Cortassa, Sonia
Publicado em 2011
“...(+), and phosphate dynamics. The model accounts for distinct respiratory fluxes from substrates of complex I...”Publicado em 2011
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20
“... cycle and the internal strain energy are obtained by a computational comparison scheme involving...”
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