Resultados da pesquisa - (( e data computer a netw ) OR ((( j oils compared cao ngoc ) OR ( 3 tail complex cause non ))))

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Probing the Role of Parasite-specific, Distant, Structural Regions on Communication and Catalysis in the Bifunctional Thymidylate Synthase- Dihydrofolate Reductase from Plasmodium...

Por Dasgupta, Tina, Anderson, Karen S.
Publicado em 2008

“... causes a 3-fold enhancement of the DHFR rate from ~14 s(−1) to ~40 s(−1). In summary, our results...”
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NOT10 and C2orf29/NOT11 form a conserved module of the CCR4-NOT complex that docks onto the NOT1 N-terminal domain

Por Bawankar, Praveen, Loh, Belinda, Wohlbold, Lara, Schmidt, Steffen, Izaurralde, Elisa
Publicado em 2013

“.... This complex catalyzes the removal of mRNA poly(A) tails, thereby repressing translation and committing an mRNA...”
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Developmental Coordination Disorder: Is Clumsy Motor Behavior Caused by a Lesion of the Brain at Early Age?

Por Hadders-Algra, Mijna
Publicado em 2003

“... of minor neurological dysfunction (MND). The data of the Groningen Perinatal Project, a long-term follow-up...”
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The polyadenosine RNA-binding protein ZC3H14 interacts with the THO complex and coordinately regulates the processing of neuronal transcripts

Por Morris, Kevin J, Corbett, Anita H
Publicado no Nucleic Acids Res (2018)

“... is ubiquitously expressed, mutation of the ZC3H14 gene causes a non-syndromic form of intellectual disability...”
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MYO3A causes human dominant deafness and interacts with protocadherin 15-CD2 isoform

Por Grati, M’hamed, Yan, Denise, Raval, Manmeet H., Walsh, Tom, Ma, Qi, Chakchouk, Imen, Kannan-Sundhari, Abhiraami, Mittal, Rahul, Masmoudi, Saber, Blanton, Susan H., Tekin, Mustafa, King, Mary-Claire, Yengo, Christopher M., Liu, Xue Zhong
Publicado no Hum Mutat (2016)

“... the interaction of MYO3A with the cytosolic tail of the integral tip-link protein protocadherin 15 (PCDH15), a...”
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Light-activation of the Archaerhodopsin H(+)-pump reverses age-dependent loss of vertebrate regeneration: sparking system-level controls in vivo

Por Adams, Dany Spencer, Tseng, Ai-Sun, Levin, Michael
Publicado em 2013

“... regrowth of a functioning spinal cord, in tails that have been inhibited by natural inactivity...”
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Iron-sulphur cluster nitrosyls, a novel class of nitric oxide generator: mechanism of vasodilator action on rat isolated tail artery.

Por Flitney, F. W., Megson, I. L., Flitney, D. E., Butler, A. R.
Publicado em 1992

“... drugs (A: tetranitrosyltetra-mu 3-sulphidotetrahedro-tetrairon; and B: heptanitrosyltri-mu 3...”
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Trypanosome CNOT10 is essential for the integrity of the NOT deadenylase complex and for degradation of many mRNAs

Por Färber, Valentin, Erben, Esteban, Sharma, Sahil, Stoecklin, Georg, Clayton, Christine
Publicado em 2013

“... in trypanosomes caused a decrease in the level of TbNOT1, detachment of TbCAF1 from the complex and pronounced...”
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TNF-α stimulation inhibits siRNA-mediated RNA interference through a mechanism involving poly-(A) tail stabilization

Por Mols, Johann, van den Berg, Arjen, Otsuka, Motoyuki, Zheng, Min, Chen, Jianming, Han, Jiahuai
Publicado em 2008

“... is an siRNA designed to target a non-ARE sequence in the TNF 3’UTR. We found that both si20 and miR16...”
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Structural and functional characterization of the PNKP–XRCC4–LigIV DNA repair complex

Por Aceytuno, R. Daniel, Piett, Cortt G., Havali-Shahriari, Zahra, Edwards, Ross A., Rey, Martial, Ye, Ruiqiong, Javed, Fatima, Fang, Shujuan, Mani, Rajam, Weinfeld, Michael, Hammel, Michal, Tainer, John A., Schriemer, David C., Lees-Miller, Susan P., Glover, J.N. Mark
Publicado no Nucleic Acids Res (2017)

“... on the PNKP phosphatase domain that may contact XRCC4–LigIV. A mutation on this surface (E326K) causes...”
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A myosin-Va tail fragment sequesters dynein light chains leading to apoptosis in melanoma cells

Por Izidoro-Toledo, T C, Borges, A C, Araújo, D D, Leitão Mazzi, D P S, Nascimento, F O, Sousa, J F, Alves, C P, Paiva, A P B, Trindade, D M, Patussi, E V, Peixoto, P M, Kinnally, K W, Espreafico, E M
Publicado em 2013

“... demonstrated that overexpression of a myosin-Va medial tail fragment (MVaf) harboring the binding site for DLC2...”
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S-nitrosylation of Surfactant Protein D as a modulator of pulmonary inflammation

Por Atochina-Vasserman, Elena N.
Publicado em 2011

“... lectins “collectins” that play a role in non-antibody-mediated innate immune responses [1]. The primary...”
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Histone code and long non-coding RNAs (lncRNAs) aberrations in lung cancer: implications in the therapy response

Por Herrera-Solorio, Abril Marcela, Armas-López, Leonel, Arrieta, Oscar, Zúñiga, Joaquín, Piña-Sánchez, Patricia, Ávila-Moreno, Federico
Publicado no Clin Epigenetics (2017)

“...Respiratory diseases hold several genome, epigenome, and transcriptional aberrations as a cause...”
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Characterization of purified Sindbis Virus nsP4 RNA-dependent RNA Polymerase activity in vitro

Por Rubach, Jon K., Wasik, Brian R., Rupp, Jonathan C., Kuhn, Richard J., Hardy, Richard W., Smith, Janet L.
Publicado em 2008

“...(A) tail of viral template RNA prevent RNA synthesis by the replicase complex containing purified nsP...”
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Contribution of ultrarare variants in mTOR pathway genes to sporadic focal epilepsies

Por Pippucci, Tommaso, Licchetta, Laura, Baldassari, Sara, Marconi, Caterina, De Luise, Monica, Myers, Candace, Nardi, Elena, Provini, Federica, Cameli, Cinzia, Minardi, Raffaella, Bacchelli, Elena, Giordano, Lucio, Crichiutti, Giovanni, d'Orsi, Giuseppe, Seri, Marco, Gasparre, Giuseppe, Mefford, Heather C., Tinuper, Paolo, Bisulli, Francesca
Publicado no Ann Clin Transl Neurol (2019)

“... in genes coding for the components of complexes regulating mechanistic Target Of Rapamycin (mTOR)complex 1...”
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Double-bromo and extraterminal (BET) domain proteins regulate dendrite morphology and mechanosensory function

Por Bagley, Joshua A., Yan, Zhiqiang, Zhang, Wei, Wildonger, Jill, Jan, Lily Yeh, Jan, Yuh Nung
Publicado em 2014

“...A complex array of genetic factors regulates neuronal dendrite morphology. Epigenetic regulation...”
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Redirecting splicing with bifunctional oligonucleotides

Por Brosseau, Jean-Philippe, Lucier, Jean-François, Lamarche, Andrée-Anne, Shkreta, Lulzim, Gendron, Daniel, Lapointe, Elvy, Thibault, Philippe, Paquet, Éric, Perreault, Jean-Pierre, Abou Elela, Sherif, Chabot, Benoit
Publicado em 2014

“... be bifunctional oligonucleotides made of an antisense portion that determines target specificity, and a non...”
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Microsatellite instability at tetranucleotide repeats in sporadic colorectal cancer in Japan

Por Yamada, Kanae, Kanazawa, Shinsaku, Koike, Junichi, Sugiyama, Hisahiko, Xu, Can, Funahashi, Kimihiko, Boland, C. Richard, Koi, Minoru, Hemmi, Hiromichi
Publicado em 2010

“... of MSI-H tumors at EMAST loci were more complex than those of non-MSI-H tumors. A tendency of positive...”
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Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5

Por Uchikawa, Emiko, Lethier, Mathilde, Malet, Hélène, Brunel, Joanna, Gerlier, Denis, Cusack, Stephen
Publicado no Mol Cell (2016)

“...RIG-I and MDA5 sense virus-derived short 5′ppp blunt-ended or long dsRNA, respectively, causing...”
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Vaccinia virus egress mediated by virus protein A36 is reliant on the F12 protein

Por Carpentier, David C. J., Van Loggerenberg, Alexander, Dieckmann, Nele M. G., Smith, Geoffrey L.
Publicado no J Gen Virol (2017)

“...-1, and three viral proteins, A36 and the F12/E2 complex, have been implicated in this process...”
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