Resultados da pesquisa - (( drugs do devel ther ) OR ((( drug doses liver thle2 ) OR ( drug dose live ther ))))

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Rationale and clinical utility of the darunavir–cobicistat combination in the treatment of HIV/AIDS

Por Putcharoen, Opass, Do, Tanya, Avihingsanon, Anchalee, Ruxrungtham, Kiat
Publicado no Drug Des Devel Ther (2015)

“... estimated glomerular filtration rate (GFR) without affecting actual GFR; 2) potential drug–drug interaction...”
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Chimeric design, synthesis, and biological assays of a new nonpeptide insulin-mimetic vanadium compound to inhibit protein tyrosine phosphatase 1B

Por Scior, Thomas, Guevara-García, José Antonio, Melendez, FJ, Abdallah, Hassan H, Do, Quoc-Tuan, Bernard, Philippe
Publicado em 2010

“... of the insulin receptor takes place. TSAG001, [V(V)O(2)(OH)(picolinamide)], was characterized by infrared (IR...”
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Design, synthesis, and antimelanogenic effects of (2-substituted phenyl-1,3-dithiolan-4-yl)methanol derivatives

Por Kim, Do Hyun, Kim, Su Jeong, Ullah, Sultan, Yun, Hwi Young, Chun, Pusoon, Moon, Hyung Ryong
Publicado no Drug Des Devel Ther (2017)

“...The authors designed and synthesized 17 (2-substituted phenyl-1,3-dithiolan-4-yl) methanol (PDTM...”
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Defensive mechanism in cholangiocarcinoma cells against oxidative stress induced by chlorin e6-based photodynamic therapy

Por Lee, Hye Myeong, Chung, Chung-Wook, Kim, Cy Hyun, Kim, Do Hyung, Kwak, Tae Won, Jeong, Young-Il, Kang, Dae Hwan
Publicado em 2014

“.../cm(2) did not significantly differ between the two CCA cell types. However, after irradiation, marked...”
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Anticancer activity of streptochlorin, a novel antineoplastic agent, in cholangiocarcinoma

Por Kwak, Tae Won, Shin, Hee Jae, Jeong, Young-Il, Han, Myoung-Eun, Oh, Sae-Ock, Kim, Hyun-Jung, Kim, Do Hyung, Kang, Dae Hwan
Publicado no Drug Des Devel Ther (2015)

“..., and expression of various protein levels. A liver metastasis model was prepared by splenic injection of HuCC-T1...”
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Design, synthesis, and anti-melanogenic effects of (E)-2-benzoyl-3-(substituted phenyl)acrylonitriles

Por Yun, Hwi Young, Kim, Do Hyun, Son, Sujin, Ullah, Sultan, Kim, Seong Jin, Kim, Yeon-Jeong, Yoo, Jin-Wook, Jung, Yunjin, Chun, Pusoon, Moon, Hyung Ryong
Publicado no Drug Des Devel Ther (2015)

“... that are safer and more effective. METHODS: (E)-2-Benzoyl-3-(substituted phenyl)acrylonitriles (BPA analogs...”
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Baracle(®) vs Baraclude(®) for 48 weeks in patients with treatment-naïve chronic hepatitis B: a comparison of efficacy and safety

Por Kim, Do Young, Kim, Ju Hyun, Tak, Won Young, Yeon, Jong Eun, Lee, Joon Hyeok, Yoon, Jung Hwan, Lee, Youn Jae, Lee, Byung Seok, Han, Byung Hoon, Lee, Han Chu
Publicado no Drug Des Devel Ther (2017)

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Concomitant food intake does not affect the efficacy of entecavir in chronic hepatitis B patients with virological response: a randomized, multicenter, noninferiority trial

Por Cho, Eun Ju, Yu, Su Jong, Kwon, So Young, Kim, Ji-Hoon, Kim, Do Young, Kim, Won, Lee, June Sung, Lee, Jin Woo, Lee, Youn Jae, Chae, Hee Bok, Yoon, Jung-Hwan
Publicado no Drug Des Devel Ther (2018)

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Analysis of pramipexole dose–response relationships in Parkinson’s disease

Por Wang, Ying, Sun, Sheng-Gang, Zhu, Sui-Qiang, Liu, Chun-Feng, Liu, Yi-Ming, Di, Qing, Shang, Hui-Fang, Ren, Yan, Xiang, Wei, Chen, Sheng-Di
Publicado no Drug Des Devel Ther (2016)

“... for Parkinson’s disease (PD). A critical dose level above which a better benefit-to-harm ratio exists has not been...”
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Dose and plasma concentration of galantamine in Alzheimer's disease - clinical application

Por Wattmo, Carina, Jedenius, Erik, Blennow, Kaj, Wallin, Åsa K
Publicado em 2013

“..., BMI, drug dose and time from drug intake were recorded. RESULTS: All patients had a measurable...”
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Antibody format and drug release rate determine the therapeutic activity of non-internalizing antibody-drug conjugates

Por Gébleux, Rémy, Wulhfard, Sarah, Casi, Giulio, Neri, Dario
Publicado no Mol Cancer Ther (2015)

“..., resulting in a drug-antibody ratio of 2. In biodistribution studies, SIP(F8)-SS-DM1 accumulated in the tumor...”
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Kinase inhibitors: a new class of antirheumatic drugs

Por Kyttaris, Vasileios C
Publicado em 2012

“... decades with the use of disease-modifying antirheumatic drugs. However, despite the use of methotrexate...”
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Treatment compliance of working persons to high-dose antimuscarinic therapies: a randomized trial

Por Kosilov, Kirill Vladimirovich, Loparev, Sergey, Kuzina, Irina, Shakirova, Olga, Zhuravskaya, Nataliya, Lobodenko, Alexandra
Publicado no Ther Adv Urol (2016)

“... in antimuscarinic (AM) drug treatment. BACKGROUND: The prevalence of urge urinary incontinence (UUI) is an average...”
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Pharmacological stimulation of p53 with low-dose doxorubicin ameliorates diet-induced nonalcoholic steatosis and steatohepatitis

Por Porteiro, Begoña, Fondevila, Marcos F., Buque, Xabier, Gonzalez-Rellan, Maria J., Fernandez, Uxia, Mora, Alfonso, Beiroa, Daniel, Senra, Ana, Gallego, Rosalia, Fernø, Johan, López, Miguel, Sabio, Guadalupe, Dieguez, Carlos, Aspichueta, Patricia, Nogueiras, Rubén
Publicado no Mol Metab (2017)

“... in the liver and in two human hepatic cells lines (HepG2 and THLE2). RESULTS: The attenuation of liver damage...”
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Pharmacological stimulation of p53 with low-dose doxorubicin ameliorates diet-induced nonalcoholic steatosis and steatohepatitis

Por Begoña Porteiro, Marcos F. Fondevila, Xabier Buque, Maria J. Gonzalez-Rellan, Uxia Fernandez, Alfonso Mora, Daniel Beiroa, Ana Senra, Rosalia Gallego, Johan Fernø, Miguel López, Guadalupe Sabio, Carlos Dieguez, Patricia Aspichueta, Rubén Nogueiras
Publicado em 2018-02-01

“... in the liver and in two human hepatic cells lines (HepG2 and THLE2). Results: The attenuation of liver damage...”
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Predictors of adherence to antiretroviral therapy among people living with HIV/AIDS in resource-limited setting of southwest ethiopia

Por Tiyou, Ayele, Belachew, Tefera, Alemseged, Fisehaye, Biadgilign, Sibhatu
Publicado em 2010

“... given for missing drugs were 9(27.3%) running out of medication/drug, 7(21.2%) being away from home...”
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Antiretroviral therapy supply chain quality control and assurance in improving people living with HIV therapeutic outcomes in Cameroon

Por Djobet, M. P. Ngogang, Singhe, David, Lohoue, Julienne, Kuaban, Christopher, Ngogang, Jeanne, Tambo, Ernest
Publicado no AIDS Res Ther (2017)

“.... ARVs drugs samples included Nevirapine, Efavirenz, and fixed dose combinations of Zidovudine...”
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Pharmacokinetics and Pharmacodynamics of the Glutamate Carboxypeptidase II Inhibitor 2-MPPA Show...

Por Vornov, James J., Wozniak, Krystyna M., Wu, Ying, Rojas, Camilo, Rais, Rana, Slusher, Barbara S.
Publicado em 2013

Assuntos: “...Drug Discovery and Translational Medicine...”
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Comparative assessment of biologics in treatment of psoriasis: drug design and clinical effectiveness of ustekinumab

Por Garcia-Valladares, Ignacio, Cuchacovich, Raquel, Espinoza, Luis R
Publicado em 2011

“... psoriasis and psoriatic arthritis, but there is still a subgroup of patients who do not respond to TNF...”
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Evaluation of the pharmacokinetic and pharmacodynamic drug interactions between cilnidipine and valsartan, in healthy volunteers

Por Lee, Jieon, Lee, Howard, Jang, Kyungho, Lim, Kyoung Soo, Shin, Dongseong, Yu, Kyung-Sang
Publicado em 2014

“..., their drug–drug interaction potential has not been investigated. This study compared the pharmacokinetic (PK...”
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