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Design, synthesis, and antimelanogenic effects of (2-substituted phenyl-1,3-dithiolan-4-yl)methanol derivatives

The authors designed and synthesized 17 (2-substituted phenyl-1,3-dithiolan-4-yl) methanol (PDTM) derivatives to find a new chemical scaffold, showing excellent tyrosinase-inhibitory activity. Their tyrosinase-inhibitory activities were evaluated against mushroom tyrosinase at 50 μM, and five of the...

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Bibliografiske detaljer
Udgivet i:Drug Des Devel Ther
Main Authors: Kim, Do Hyun, Kim, Su Jeong, Ullah, Sultan, Yun, Hwi Young, Chun, Pusoon, Moon, Hyung Ryong
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358987/
https://ncbi.nlm.nih.gov/pubmed/28352157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S131538
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