BDDCS Applied to Over 900 Drugs

Por Benet, Leslie Z., Broccatelli, Fabio, Oprea, Tudor I.
Publicado em 2011

Drug-induced liver injury: a clinical update

Por Ghabril, Marwan, Chalasani, Naga, Björnsson, Einar
Publicado em 2010

Quantum mechanics implementation in drug-design workflows: does it really help?

Por Arodola, Olayide A, Soliman, Mahmoud ES
Publicado no Drug Des Devel Ther (2017)

Quantum mechanics implementation in drug-design workflows: does it really help? [Corrigendum]

Publicado no Drug Des Devel Ther (2017)

The effect of trimethoprim on CYP2C8 mediated rosiglitazone metabolism in human liver microsomes and healthy subjects

Por Hruska, M W, Amico, J A, Langaee, T Y, Ferrell, R E, Fitzgerald, S M, Frye, R F
Publicado em 2005

A transcriptomics data-driven gene space accurately predicts liver cytopathology and drug-induced liver injury

Por Kohonen, Pekka, Parkkinen, Juuso A., Willighagen, Egon L., Ceder, Rebecca, Wennerberg, Krister, Kaski, Samuel, Grafström, Roland C.
Publicado no Nat Commun (2017)

AGEING AND DRUG-INDUCED LIVER INJURY: INSIGHTS FROM ANIMAL STUDIES

Por Mach, J., Huizer-Pajkos, A., Mitchell, S., Phillips, L., Kane, A.E., de Cabo, R., Le Couteur, D.G., Hilmer, S.N.
Publicado no Innov Aging (2017)

An open randomized clinical trial in comparing two artesunate-based combination treatments on Plasmodium falciparum malaria in Nigerian children: artesunate/sulphamethoxypyrazine/pyrimethamine (fixed dose over 24 hours) versus artesunate/amodiaquine (fixed dose over 48 hours)

Por Ayede, Idowu Adejumoke, Falade, Adegoke Gbadegesin, Sowunmi, Akintunde, Jansen, Frans Herwig
Publicado em 2010

The need for antibiotic stewardship and treatment standardization in the care of cirrhotic patients with spontaneous bacterial peritonitis – a retrospective cohort study examining the effect of ceftriaxone dosing [v...

Por Laura Mazer, Elliot B. Tapper, Gail Piatkowski, Michelle Lai
Publicado em 2014-07-01

Potential deleterious effects of paracetamol dose regime used in Nigeria versus that of the United States of America

Por Samuel James Offor, Cecilia Nwadiuto Amadi, Ifeyinwa Chijioke-Nwauche, Jose E. Manautou, Orish E. Orisakwe
Publicado em 2022-01-01

Evidence-Based Recommendations to Improve the Safe Use of Drugs in Patients with Liver Cirrhosis

Por Weersink, Rianne A., Bouma, Margriet, Burger, David M., Drenth, Joost P. H., Harkes-Idzinga, S. Froukje, Hunfeld, Nicole G. M., Metselaar, Herold J., Monster-Simons, Margje H., Taxis, Katja, Borgsteede, Sander D.
Publicado no Drug Saf (2018)

A Mechanistic Framework for In Vitro–In Vivo Extrapolation of Liver Membrane Transporters...

Por Jamei, M., Bajot, F., Neuhoff, S., Barter, Z., Yang, J., Rostami-Hodjegan, A., Rowland-Yeo, K.
Publicado em 2013

A Microarray Analysis of the Temporal Response of Liver to Methylprednisolone: A Comparative Analysis of Two Dosing Regimens

Por Almon, Richard R., DuBois, Debra C., Jusko, William J.
Publicado em 2007

Modeling Therapeutic Antibody–Small Molecule Drug-Drug Interactions Using a Three-Dimensional Perfusable Human Liver Coculture Platform

Por Long, Thomas J., Cosgrove, Patrick A., Dunn, Robert T., Stolz, Donna B., Hamadeh, Hisham, Afshari, Cynthia, McBride, Helen, Griffith, Linda G.
Publicado no Drug Metab Dispos (2016)

Multi-component infusion hepatoprotectors for liver damage

Por E. I. Sas, V. B. Grinevich
Publicado em 2019-05-01

The risk of acute liver injury associated with cimetidine and other acid-suppressing anti-ulcer drugs

Por García Rodríguez, Luis A., Wallander, Mari-Ann, Stricker, Bruno H. Ch.
Publicado em 1997

Drug-induced liver injury in inflammatory bowel disease: 1-year prospective observational study

Por Koller, Tomas, Galambosova, Martina, Filakovska, Simona, Kubincova, Michaela, Hlavaty, Tibor, Toth, Jozef, Krajcovicova, Anna, Payer, Juraj
Publicado no World J Gastroenterol (2017)

Effects of terlipressin and double-dose octreotide on hepatic venous pressure gradient in patients with liver cirrhosis: a comparative study

Por FENG Qingling, FENG Zemin, ZHANG Chunqing
Publicado em 2016-04-01

Liver microsomal drug-metabolizing enzyme activity: enhancement by blockade of degradative processes in promethazine-treated rats.

Por Fernández, G., Villarruel, M. C., Bernacchi, A., de Castro, C. R., Castro, J. A.
Publicado em 1981

New Dosing Strategies for an Old Antibiotic: Pharmacodynamics of Front-Loaded Regimens of Colistin...

Por Rao, Gauri G., Ly, Neang S., Haas, Curtis E., Garonzik, Samira, Forrest, Alan, Bulitta, Jurgen B., Kelchlin, Pamela A., Holden, Patricia N., Nation, Roger L., Li, Jian, Tsuji, Brian T.
Publicado em 2014