Resultados da pesquisa - (( drug _ develop them ) or ( drug disease derived three ))*

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Naphthoquinone Derivatives as Scaffold to Develop New Drugs for Tuberculosis Treatment

Por Halicki, Priscila C. B., Ferreira, Laís A., De Moura, Kelly C. G., Carneiro, Paula F., Del Rio, Karina P., Carvalho, Tatiane dos S. C., Pinto, Maria do C. F. R., da Silva, Pedro E. A., Ramos, Daniela F.
Publicado no Front Microbiol (2018)

“...Despite being a curable disease, tuberculosis (TB) remains a public health problem worldwide mainly...”
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Synthetic berberine derivatives as potential new drugs

Por Mensura Sied Filli, Ahmed Abdalla Ibrahim, Samuel Kesse, Md Aquib, Kofi Oti Boakye-Yiadom, Muhammad Asim Farooq, Faisal Raza, Yubin Zhang, Bo Wang
Publicado em 2022-04-01

Assuntos: “...Synthetic derivatives...”
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First-in-Human Case Study: Pregnancy in Women With Crohn’s Perianal Fistula Treated With Adipose-Derived Stem Cells: A Safety Study

Por Sanz-Baro, Raquel, García-Arranz, Mariano, Guadalajara, Hector, de la Quintana, Paloma, Herreros, Maria Dolores, García-Olmo, Damián
Publicado no Stem Cells Transl Med (2015)

Assuntos: “...Cell-Based Drug Development, Screening, and Toxicology...”
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Aggressive treatment in paediatric or young patients with drug-induced hypersensitivity syndrome (DiHS)/drug reaction with eosinophilia and systemic symptoms (DRESS) is associated with future development of type III polyglandular autoimmune syndrome

Por Morita, Chiyo, Yanase, Tetsuji, Shiohara, Tetsuo, Aoyama, Yumi
Publicado no BMJ Case Rep (2018)

Assuntos: “...Findings That Shed New Light on the Possible Pathogenesis of a Disease or an Adverse Effect...”
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Failures to further developing orphan medicinal products after designation granted in Europe...

Por Giannuzzi, Viviana, Landi, Annalisa, Bosone, Enrico, Giannuzzi, Floriana, Nicotri, Stefano, Torrent-Farnell, Josep, Bonifazi, Fedele, Felisi, Mariagrazia, Bonifazi, Donato, Ceci, Adriana
Publicado no BMJ Open (2017)

“... the development process, since no data on 48.1% of them were published and the 3.2% did not progress beyond...”
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Drug Delivery of siRNA Therapeutics

Publicado em 2020

Assuntos: “...drug co-delivery...”
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Developing Stem Cell-Based Therapies For Neural Repair

Por Lachlan Thompson, Clare Parish
Publicado no Frontiers Research Topics (2015)

Assuntos: “...disease modelling...”
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Potential of magnetic nanoparticles for targeted drug delivery

Por Yang, Hung-Wei, Hua, Mu-Yi, Liu, Hao-Li, Huang, Chiung-Yin, Wei, Kuo-Chen
Publicado em 2012

“..., making them useful for drug delivery, targeted therapy, magnetic resonance imaging, transfection...”
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LabeledIn: Cataloging Labeled Indications for Human Drugs

Por Khare, Ritu, Li, Jiao, Lu, Zhiyong
Publicado no J Biomed Inform (2014)

“...Drug-disease treatment relationships, i.e., which drug(s) are indicated to treat which disease...”
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Cell-based models to predict human hepatotoxicity of drugs

Por MJ Gómez-Lechón, L Tolosa, Donato MT
Publicado no Revista de Toxicología (2014)

“...Drug-induced liver injury is a significant leading cause of liver disease and post-market attrition...”
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Chitins and Chitosans as Immunoadjuvants and Non-Allergenic Drug Carriers

Por Muzzarelli, Riccardo A. A.
Publicado em 2010

“... non-specific host resistance against bacterial and viral infections, and anti-tumor activity; (iii...”
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PhytoNanotechnology: Enhancing Delivery of Plant Based Anti-cancer Drugs

Por Tabassum Khan, Pranav Gurav
Publicado em 2018-02-01

Assuntos: “...drug delivery systems...”
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PhytoNanotechnology: Enhancing Delivery of Plant Based Anti-cancer Drugs

Por Khan, Tabassum, Gurav, Pranav
Publicado no Front Pharmacol (2018)

“... that exist in nature. Three new anti-cancer drugs introduced in 2007, viz. trabectedin, epothilone derivative...”
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Drug Repurposing by Simulating Flow Through Protein–Protein Interaction Networks

Por Manczinger, M, Bodnár, VÁ, Papp, BT, Bolla, SB, Szabó, K, Balázs, B, Csányi, E, Szél, E, Erős, G, Kemény, L
Publicado no Clin Pharmacol Ther (2017)

“... substances, identified 51 drugs that were potentially effective, and selected three of them for experimental...”
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Drug versus vaccine investment: a modelled comparison of economic incentives

Por Régnier, Stéphane A, Huels, Jasper
Publicado em 2013

“... disease that affects children, and the interactions between them. RESULTS: The model confirmed...”
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From Synthetic Fragments of Endogenous Three-Finger Proteins to Potential Drugs

Por Kryukova, Elena V., Egorova, Natalia S., Kudryavtsev, Denis S., Lebedev, Dmitry S., Spirova, Ekaterina N., Zhmak, Maxim N., Garifulina, Aleksandra I., Kasheverov, Igor E., Utkin, Yuri N., Tsetlin, Victor I.
Publicado no Front Pharmacol (2019)

“... nAChRs are well-known targets for developing analgesics and drugs against neurodegenerative diseases...”
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A new chemoinformatics approach with improved strategies for effective predictions of potential drugs

Por Ming Hao, Stephen H. Bryant, Yanli Wang
Publicado em 2018-10-01

“... chemoinformatics approach derived from neighbor-based collaborative filtering (NBCF) to infer potential drug...”
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New and Investigational Antiretroviral Drugs for HIV Infection: Mechanisms of Action and Early Research Findings

Por Saag, Michael S.
Publicado no Top Antivir Med (2016)

“...Numerous investigational antiretroviral agents are in clinical development. Among them...”
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Preclinical Assessment of the Anticancer Drug Response of Plexiform Neurofibroma Tissue Using Primary Cultures

Por Jiang, Wei, Mautner, Victor-F., Friedrich, Reinhard E., Kluwe, Lan
Publicado no J Clin Neurol (2015)

“... further development of an application for preclinical drug selection and drug discovery....”
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Highly Potent Inhibitors of Proprotein Convertase Furin as Potential Drugs for Treatment of Infectious Diseases

Por Becker, Gero L., Lu, Yinghui, Hardes, Kornelia, Strehlow, Boris, Levesque, Christine, Lindberg, Iris, Sandvig, Kirsten, Bakowsky, Udo, Day, Robert, Garten, Wolfgang, Steinmetzer, Torsten
Publicado em 2012

“... drug development, in particular for the treatment of infectious diseases....”
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