Resultados da pesquisa - ((((drug doses) or (drugs dual))) or (drug dose)) devel ther*

1

Single- and multiple-dose tolerability, safety, pharmacokinetics, and pharmacodynamics of the dual...

Por Sidharta, Patricia N, Melchior, Meggane, Kankam, Martin K, Dingemanse, Jasper
Publicado no Drug Des Devel Ther (2019)

“... with doses ≥25 mg. Time-matched analysis of electrocardiogram (ECG) parameters did not suggest drug-induced...”
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2

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Pharmacokinetics and bioavailability of oxycodone and acetaminophen following single-dose...

Por Devarakonda, Krishna, Morton, Terri, Margulis, Rachel, Giuliani, Michael, Barrett, Thomas
Publicado em 2014

“... was performed. METHODS: This Phase I study used an open-label randomized single-dose three-period six-sequence...”
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3

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Spotlight on valsartan–sacubitril fixed-dose combination for heart failure: the evidence to date

Por Vilela-Martin, José Fernando
Publicado no Drug Des Devel Ther (2016)

“... ejection fraction, giving emphasis to a drug that has a dual-acting inhibition of the neprilysin and renin...”
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Development of 13-Cys-BBR as an Agent Having Dual Action of Anti-Thrombosis and Anti-Inflammation

Por Li, Guanyu, Wang, Tong, Zhang, Xiaoyi, Zhao, Shurui, Wang, Yaonan, Wu, Jianhui, Peng, Shiqi, Zhao, Ming
Publicado no Drug Des Devel Ther (2020)

“... edema. RESULTS: At oral dose of 66.7 nmol/kg, 13-Cys-BBR, but not BBR, inhibited the rats to form both...”
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Efficacy of the dual PI3K and mTOR inhibitor NVP-BEZ235 in combination with imatinib mesylate against chronic myelogenous leukemia cell lines

Por Xin, Pengliang, Li, Chuntuan, Zheng, Yan, Peng, Qunyi, Xiao, Huifang, Huang, Yuanling, Zhu, Xiongpeng
Publicado no Drug Des Devel Ther (2017)

“... is a therapy target of cancer. We aimed to confirm the effect of dual PI3K/mTOR inhibitor NVP-BEZ235...”
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The Safety and Efficacy of Ultrasound-Guided Bilateral Dual Transversus Abdominis Plane (BD-TAP...

Por Zhang, Jun, Liu, Tieshuai, Zhou, Haiyan, Fei, Yue, Yu, Xin
Publicado no Drug Des Devel Ther (2020)

“... is a promising regional analgesic technique. However, the correct guidelines regarding the dose...”
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Very rapid virologic response and early HCV response kinetics, as quick measures to compare efficacy and guide a personalized response-guided therapy

Por Yakoot, Mostafa, Abdo, Alaa M, Yousry, Ahmed, Helmy, Sherine
Publicado no Drug Des Devel Ther (2016)

“... sofosbuvir products for the degree and speed of virologic response to a dual anti-hepatitis C virus (HCV...”
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Profile of suvorexant in the management of insomnia

Por Sutton, Eliza L
Publicado no Drug Des Devel Ther (2015)

“... with strong CYP3A inhibitors. Drug levels are higher in women and obese people; hence, dosing should...”
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New developments in the combination treatment of COPD: focus on umeclidinium/vilanterol

Por Cazzola, Mario, Segreti, Andrea, Matera, Maria Gabriella
Publicado em 2013

“... is an effective once-daily dual bronchodilator fixed-dose combination in the treatment of COPD. However...”
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Neuroprotective effects of dexmedetomidine against isoflurane-induced neuronal injury via glutamate regulation in neonatal rats

Por Wang, Xue, Shan, Yangyang, Tang, Zhiyin, Gao, Linlin, Liu, Hongtao
Publicado no Drug Des Devel Ther (2018)

“...% isoflurane for 4 h); and isoflurane + dual doses of dexmedetomidine (25 µg/kg, 20 min before and 2 h after...”
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The very-rapid and the ultra-rapid virologic response to two treatment options in patients with chronic hepatitis C: an interim report of a prospective randomized comparative effec...

Por Yakoot, Mostafa, Abdo, Alaa M, Yousry, Ahmed, Helmy, Sherine
Publicado no Drug Des Devel Ther (2015)

“... for the degree and speed of virologic response to a dual antiviral treatment protocol within the first 2 weeks...”
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Pharmacokinetics of conivaptan use in patients with severe hepatic impairment

Por Marbury, Thomas, Fox, Jerry, Kaelin, Byron, Pavliv, Leo
Publicado no Drug Des Devel Ther (2017)

“...PURPOSE: Conivaptan is an intravenous dual V(1A)/V(2) vasopressin antagonist approved...”
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Hesperetin-5,7,3ʹ-O-Trimethylether Dually Inhibits Phosphodiesterase 3/4 and Methacholine-Induced Airway Hyperresponsiveness in Sensitized and Challenged Mice

Por Shih, Chung-Hung, Wang, Wen-Hung, Chen, Chi-Ming, Ko, Wun-Chang
Publicado no Drug Des Devel Ther (2020)

“... been reported to be a dual phosphodiesterase (PDE)3/4 inhibitor. We investigated its inhibitory effects...”
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Regulations of miR-183-5p and Snail-Mediated Shikonin-Reduced Epithelial-Mesenchymal Transition in Cervical Cancer Cells

Por Tang, Qing, Liu, Lihua, Zhang, Hongyan, Xiao, Jing, Hann, Swei Sunny
Publicado no Drug Des Devel Ther (2020)

“... Dual Luminescence Assay Kit. The transient transfection experiments were used for silencing of E...”
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