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Pharmacokinetics of conivaptan use in patients with severe hepatic impairment

PURPOSE: Conivaptan is an intravenous dual V(1A)/V(2) vasopressin antagonist approved for the treatment of euvolemic and hypervolemic hyponatremia. Earlier studies showed that patients with moderate liver disease could be safely treated with conivaptan by reducing the dose by 50%, whereas patients w...

詳細記述

保存先:
書誌詳細
出版年:Drug Des Devel Ther
主要な著者: Marbury, Thomas, Fox, Jerry, Kaelin, Byron, Pavliv, Leo
フォーマット: Artigo
言語:Inglês
出版事項: Dove Medical Press 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5315214/
https://ncbi.nlm.nih.gov/pubmed/28243060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S125459
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