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Pharmacokinetics of Voxelotor in Patients With Renal and Hepatic Impairment

Two open‐label studies assessed the safety, tolerability, and pharmacokinetics of Oxbryta (voxelotor) in subjects with hepatic or renal impairment. Eight subjects with severe renal impairment (estimated glomerular filtration rate <30 mL/min/1.73 m(2)) and 8 healthy age‐, sex‐, and body mass index...

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Detalhes bibliográficos
Publicado no:J Clin Pharmacol
Main Authors: Preston, Richard A., Marbury, Thomas, Balaratnam, Ganesh, Green, Michelle, Dixon, Sandy, Lehrer‐Graiwer, Josh, Washington, Carla
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7984382/
https://ncbi.nlm.nih.gov/pubmed/33084052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.1757
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