Characterization of the Effect of Renal Impairment on Upadacitinib Pharmacokinetics

Upadacitinib is a novel selective Janus kinase 1 inhibitor developed for treatment of rheumatoid arthritis and other autoimmune diseases. The objective of this study was to assess the pharmacokinetics and safety of a single upadacitinib dose in subjects with normal renal function and in subjects wit...

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Bibliographic Details
Published in:J Clin Pharmacol
Main Authors: Mohamed, Mohamed‐Eslam F., Trueman, Sheryl, Feng, Tian, Anderson, Jaclyn, Marbury, Thomas C., Othman, Ahmed A.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2019
Subjects:
Special Populations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6590375/
https://ncbi.nlm.nih.gov/pubmed/30633369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.1375
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