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Characterization of the Effect of Renal Impairment on Upadacitinib Pharmacokinetics
Upadacitinib is a novel selective Janus kinase 1 inhibitor developed for treatment of rheumatoid arthritis and other autoimmune diseases. The objective of this study was to assess the pharmacokinetics and safety of a single upadacitinib dose in subjects with normal renal function and in subjects wit...
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| Veröffentlicht in: | J Clin Pharmacol |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6590375/ https://ncbi.nlm.nih.gov/pubmed/30633369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.1375 |
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