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Characterization of the Effect of Renal Impairment on Upadacitinib Pharmacokinetics

Upadacitinib is a novel selective Janus kinase 1 inhibitor developed for treatment of rheumatoid arthritis and other autoimmune diseases. The objective of this study was to assess the pharmacokinetics and safety of a single upadacitinib dose in subjects with normal renal function and in subjects wit...

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Vydáno v:J Clin Pharmacol
Hlavní autoři: Mohamed, Mohamed‐Eslam F., Trueman, Sheryl, Feng, Tian, Anderson, Jaclyn, Marbury, Thomas C., Othman, Ahmed A.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6590375/
https://ncbi.nlm.nih.gov/pubmed/30633369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.1375
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